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Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair.
Layer JV, Debaize L, Van Scoyk A, House NC, Brown AJ, Liu Y, Stevenson KE, Hemann M, Roberts SA, Price BD, Weinstock DM, Day TA. Layer JV, et al. Among authors: hemann m. Proc Natl Acad Sci U S A. 2020 Nov 3;117(44):27566-27577. doi: 10.1073/pnas.2014176117. Epub 2020 Oct 19. Proc Natl Acad Sci U S A. 2020. PMID: 33077594 Free PMC article.
Defining principles of combination drug mechanisms of action.
Pritchard JR, Bruno PM, Gilbert LA, Capron KL, Lauffenburger DA, Hemann MT. Pritchard JR, et al. Among authors: hemann mt. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):E170-9. doi: 10.1073/pnas.1210419110. Epub 2012 Dec 18. Proc Natl Acad Sci U S A. 2013. PMID: 23251029 Free PMC article.
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents.
Lossos C, Liu Y, Kolb KE, Christie AL, Van Scoyk A, Prakadan SM, Shigemori K, Stevenson KE, Morrow S, Plana OD, Fraser C, Jones KL, Liu H, Pallasch CP, Modiste R, Nguyen QD, Craig JW, Morgan EA, Vega F, Aster JC, Sarosiek KA, Shalek AK, Hemann MT, Weinstock DM. Lossos C, et al. Among authors: hemann mt. Cancer Discov. 2019 Jul;9(7):944-961. doi: 10.1158/2159-8290.CD-18-1393. Epub 2019 Apr 30. Cancer Discov. 2019. PMID: 31040105 Free PMC article.
A dynamic view of chemotherapy effectiveness.
Liu Y, Hemann MT. Liu Y, et al. Nature. 2019 Aug;572(7769):321-322. doi: 10.1038/d41586-019-02336-7. Nature. 2019. PMID: 31406309 No abstract available.
149 results