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Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity.
Karaboga H, Huang W, Srivastava S, Widmann S, Addanki S, Gamage KT, Mazhar Z, Ebalunode JO, Briggs JM, Gustafsson JÅ, Filgueira CS, Gilbertson SR, Lin CY. Karaboga H, et al. Among authors: gilbertson sr. ACS Chem Biol. 2020 Nov 20;15(11):2916-2928. doi: 10.1021/acschembio.0c00546. Epub 2020 Oct 19. ACS Chem Biol. 2020. PMID: 33074669
Discovery of vascular Rho kinase (ROCK) inhibitory peptides.
Abbasgholizadeh R, Zhang H, Craft JW Jr, Bryan RM Jr, Bark SJ, Briggs JM, Fox RO, Agarkov A, Zimmer WE, Gilbertson SR, Schwartz RJ. Abbasgholizadeh R, et al. Among authors: gilbertson sr. Exp Biol Med (Maywood). 2019 Aug;244(11):940-951. doi: 10.1177/1535370219849581. Epub 2019 May 27. Exp Biol Med (Maywood). 2019. PMID: 31132884 Free PMC article.
Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior.
Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW Jr, Laezza FM, Watson CS, Briggs JM, Cunningham KA. Anastasio NC, et al. Among authors: gilbertson sr. J Neurosci. 2013 Jan 23;33(4):1615-30. doi: 10.1523/JNEUROSCI.2656-12.2013. J Neurosci. 2013. PMID: 23345234 Free PMC article.
Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction.
Cunningham KA, Anastasio NC, Fox RG, Stutz SJ, Bubar MJ, Swinford SE, Watson CS, Gilbertson SR, Rice KC, Rosenzweig-Lipson S, Moeller FG. Cunningham KA, et al. Among authors: gilbertson sr. ACS Chem Neurosci. 2013 Jan 16;4(1):110-21. doi: 10.1021/cn300072u. Epub 2012 Aug 11. ACS Chem Neurosci. 2013. PMID: 23336050 Free PMC article.
68 results