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Page 1
Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity.
Karaboga H, Huang W, Srivastava S, Widmann S, Addanki S, Gamage KT, Mazhar Z, Ebalunode JO, Briggs JM, Gustafsson JÅ, Filgueira CS, Gilbertson SR, Lin CY. Karaboga H, et al. Among authors: filgueira cs. ACS Chem Biol. 2020 Nov 20;15(11):2916-2928. doi: 10.1021/acschembio.0c00546. Epub 2020 Oct 19. ACS Chem Biol. 2020. PMID: 33074669
The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.
Benod C, Villagomez R, Filgueira CS, Hwang PK, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P. Benod C, et al. Among authors: filgueira cs. PLoS One. 2014 Jun 17;9(6):e99440. doi: 10.1371/journal.pone.0099440. eCollection 2014. PLoS One. 2014. PMID: 24936658 Free PMC article.
A screening cascade to identify ERβ ligands.
Filgueira CS, Benod C, Lou X, Gunamalai PS, Villagomez RA, Strom A, Gustafsson JÅ, Berkenstam AL, Webb P. Filgueira CS, et al. Nucl Recept Signal. 2014 Nov 4;12:e003. doi: 10.1621/nrs.12003. eCollection 2014. Nucl Recept Signal. 2014. PMID: 25422593 Free PMC article.
Zonal Intratumoral Delivery of Nanoparticles Guided by Surface Functionalization.
Terracciano R, Carcamo-Bahena Y, Royal ALR, Messina L, Delk J, Butler EB, Demarchi D, Grattoni A, Wang Z, Cristini V, Dogra P, Filgueira CS. Terracciano R, et al. Among authors: filgueira cs. Langmuir. 2022 Nov 15;38(45):13983-13994. doi: 10.1021/acs.langmuir.2c02319. Epub 2022 Nov 1. Langmuir. 2022. PMID: 36318182 Free PMC article.
PPARγ partial agonist GQ-16 strongly represses a subset of genes in 3T3-L1 adipocytes.
Milton FA, Cvoro A, Amato AA, Sieglaff DH, Filgueira CS, Arumanayagam AS, de Lima Mdo C, Pitta IR, de Assis Rocha Neves F, Webb P. Milton FA, et al. Among authors: filgueira cs. Biochem Biophys Res Commun. 2015 Aug 28;464(3):718-23. doi: 10.1016/j.bbrc.2015.07.011. Epub 2015 Jul 10. Biochem Biophys Res Commun. 2015. PMID: 26168725
Three-dimensional printed polymeric system to encapsulate human mesenchymal stem cells differentiated into islet-like insulin-producing aggregates for diabetes treatment.
Sabek OM, Farina M, Fraga DW, Afshar S, Ballerini A, Filgueira CS, Thekkedath UR, Grattoni A, Gaber AO. Sabek OM, et al. Among authors: filgueira cs. J Tissue Eng. 2016 Apr 21;7:2041731416638198. doi: 10.1177/2041731416638198. eCollection 2016 Jan-Dec. J Tissue Eng. 2016. PMID: 27152147 Free PMC article.
28 results