Ghelardini C - Search Results

1

(E)-3-Furan-2-yl-N-p-tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation.

Arias HR, Ghelardini C, Lucarini E, Tae HS, Yousuf A, Marcovich I, Manetti D, Romanelli MN, Elgoyhen AB, Adams DJ, Di Cesare Mannelli L. Arias HR, et al. Among authors: ghelardini c. ACS Chem Neurosci. 2020 Nov 4;11(21):3603-3614. doi: 10.1021/acschemneuro.0c00476. Epub 2020 Oct 19. ACS Chem Neurosci. 2020. PMID: 33073974

2

Memory facilitation and stimulation of endogenous nerve growth factor synthesis by the acetylcholine releaser PG-9.

Ghelardini C, Galeotti N, Bartolini A, Furukawa S, Nitta A, Manetti D, Gualtieri F. Ghelardini C, et al. Jpn J Pharmacol. 1998 Nov;78(3):245-51. doi: 10.1254/jjp.78.245. Jpn J Pharmacol. 1998. PMID: 9869257 Free article.

3

Molecular simplification of 1,4-diazabicyclo[4.3.0]nonan-9-ones gives piperazine derivatives that maintain high nootropic activity.

Manetti D, Ghelardini C, Bartolini A, Dei S, Galeotti N, Gualtieri F, Romanelli MN, Teodori E. Manetti D, et al. Among authors: ghelardini c. J Med Chem. 2000 Nov 16;43(23):4499-507. doi: 10.1021/jm000972h. J Med Chem. 2000. PMID: 11087574

4

Design and study of piracetam-like nootropics, controversial members of the problematic class of cognition-enhancing drugs.

Gualtieri F, Manetti D, Romanelli MN, Ghelardini C. Gualtieri F, et al. Among authors: ghelardini c. Curr Pharm Des. 2002;8(2):125-38. doi: 10.2174/1381612023396582. Curr Pharm Des. 2002. PMID: 11812254 Review.

5

Menthol: a natural analgesic compound.

Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A, Ghelardini C. Galeotti N, et al. Among authors: ghelardini c. Neurosci Lett. 2002 Apr 12;322(3):145-8. doi: 10.1016/s0304-3940(01)02527-7. Neurosci Lett. 2002. PMID: 11897159

6

AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).

Galeotti N, Ghelardini C, Pittaluga A, Pugliese AM, Bartolini A, Manetti D, Romanelli MN, Gualtieri F. Galeotti N, et al. Among authors: ghelardini c. Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45. doi: 10.1007/s00210-003-0812-6. Epub 2003 Nov 5. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14600801

7

Design, synthesis, and preliminary pharmacological evaluation of 4-aminopiperidine derivatives as N-type calcium channel blockers active on pain and neuropathic pain.

Teodori E, Baldi E, Dei S, Gualtieri F, Romanelli MN, Scapecchi S, Bellucci C, Ghelardini C, Matucci R. Teodori E, et al. Among authors: ghelardini c. J Med Chem. 2004 Nov 18;47(24):6070-81. doi: 10.1021/jm049923l. J Med Chem. 2004. PMID: 15537361

8

Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins.

Manetti D, Di Cesare Mannelli L, Dei S, Galeotti N, Ghelardini C, Romanelli MN, Scapecchi S, Teodori E, Pacini A, Bartolini A, Gualtieri F. Manetti D, et al. Among authors: ghelardini c. J Med Chem. 2005 Oct 6;48(20):6491-503. doi: 10.1021/jm050498l. J Med Chem. 2005. PMID: 16190775

9

Enantioselective synthesis and preliminary pharmacological evaluation of the enantiomers of unifiram (DM232), a potent cognition-enhancing agent.

Martini E, Ghelardini C, Bertucci C, Dei S, Gualtieri F, Guandalini L, Manetti D, Scapecchi S, Teodori E, Romanelli MN. Martini E, et al. Among authors: ghelardini c. Med Chem. 2005 Sep;1(5):473-80. doi: 10.2174/1573406054864142. Med Chem. 2005. PMID: 16787332

10

Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.

Romanelli MN, Galeotti N, Ghelardini C, Manetti D, Martini E, Gualtieri F. Romanelli MN, et al. Among authors: ghelardini c. CNS Drug Rev. 2006 Spring;12(1):39-52. doi: 10.1111/j.1527-3458.2006.00039.x. CNS Drug Rev. 2006. PMID: 16834757 Free PMC article. Review.

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