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Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin.
Lee KJ, Chang WL, Chen X, Valiyaveettil J, Ramirez-Alcantara V, Gavin E, Musiyenko A, Madeira da Silva L, Annamdevula NS, Leavesley SJ, Ward A, Mattox T, Lindsey AS, Andrews J, Zhu B, Wood C, Neese A, Nguyen A, Berry K, Maxuitenko Y, Moyer MP, Nurmemmedov E, Gorman G, Coward L, Zhou G, Keeton AB, Cooper HS, Clapper ML, Piazza GA. Lee KJ, et al. Among authors: ward a. Cancer Prev Res (Phila). 2021 Nov;14(11):995-1008. doi: 10.1158/1940-6207.CAPR-21-0208. Epub 2021 Sep 28. Cancer Prev Res (Phila). 2021. PMID: 34584001 Free PMC article.
Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.
Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Among authors: ward a. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.
Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer.
Borneman RM, Gavin E, Musiyenko A, Richter W, Lee KJ, Crossman DK, Andrews JF, Wilhite AM, McClellan S, Aragon I, Ward AB, Chen X, Keeton AB, Berry K, Piazza GA, Scalici JM, da Silva LM. Borneman RM, et al. Among authors: ward ab. J Ovarian Res. 2022 Nov 2;15(1):120. doi: 10.1186/s13048-022-01050-9. J Ovarian Res. 2022. PMID: 36324187 Free PMC article.
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Maxuitenko Y, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V, Abdelkarim H, Boyd MR, Gorman GS, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. Among authors: ward ab. bioRxiv [Preprint]. 2024 Jun 5:2023.05.17.541233. doi: 10.1101/2023.05.17.541233. bioRxiv. 2024. PMID: 38328254 Free PMC article. Preprint.
Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.
Brinkkemper M, Kerster G, Brouwer PJM, Tran AS, Torres JL, Ettema RA, Nijhuis H, Allen JD, Zhu W, Gao H, Lee WH, Bijl TPL, Snitselaar JL, Burger JA, Bontjer I, Olijhoek W, Ravichandran R, van Breemen MJ, Del Moral-Sánchez I, Derking R, Sliepen K, Ozorowski G, Crispin M, Montefiori DC, Claireaux M, Ward AB, van Gils MJ, King NP, Sanders RW. Brinkkemper M, et al. Among authors: ward ab. PLoS Pathog. 2024 Oct 3;20(10):e1012558. doi: 10.1371/journal.ppat.1012558. eCollection 2024 Oct. PLoS Pathog. 2024. PMID: 39361585 Free PMC article.
Assessing AF2's ability to predict structural ensembles of proteins.
Riccabona JR, Spoendlin FC, Fischer AM, Loeffler JR, Quoika PK, Jenkins TP, Ferguson JA, Smorodina E, Laustsen AH, Greiff V, Forli S, Ward AB, Deane CM, Fernández-Quintero ML. Riccabona JR, et al. Among authors: ward ab. Structure. 2024 Sep 20:S0969-2126(24)00370-8. doi: 10.1016/j.str.2024.09.001. Online ahead of print. Structure. 2024. PMID: 39332396
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin.
Berndsen ZT, Akhtar M, Thapa M, Vickers TJ, Schmitz A, Torres JL, Baboo S, Kumar P, Khatoon N, Sheikh A, Hamrick M, Diedrich JK, Martinez-Bartolome S, Garrett PT, Yates JR 3rd, Turner JS, Laird RM, Poly F, Porter CK, Copps J, Ellebedy AH, Ward AB, Fleckenstein JM. Berndsen ZT, et al. Among authors: ward ab. PLoS Pathog. 2024 Sep 16;20(9):e1012241. doi: 10.1371/journal.ppat.1012241. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39283948 Free PMC article.
491 results