Hagiwara-Nagasawa M - Search Results

1

Analysis of electropharmacological and proarrhythmic effects of donepezil using the halothane-anesthetized intact dogs and the conscious chronic atrioventricular block ones.

Hagiwara-Nagasawa M, Kambayashi R, Goto A, Nunoi Y, Izumi-Nakaseko H, Chiba K, Wada T, Takei Y, Matsumoto A, Sugiyama A. Hagiwara-Nagasawa M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2021 Apr;394(4):581-589. doi: 10.1007/s00210-020-01997-w. Epub 2020 Oct 16. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 33064166

2

Analysis of proarrhythmic potential of an atypical antipsychotic drug paliperidone in the halothane-anesthetized dogs.

Chiba K, Wada T, Nakamura Y, Cao X, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Ando K, Tanaka K, Naito AT, Sugiyama A. Chiba K, et al. J Pharmacol Sci. 2017 Aug;134(4):239-246. doi: 10.1016/j.jphs.2017.08.002. Epub 2017 Aug 12. J Pharmacol Sci. 2017. PMID: 28844424 Free article.

3

In vivo Analysis of the Anti-atrial Fibrillatory, Proarrhythmic and Cardiodepressive Profiles of Dronedarone as a Guide for Safety Pharmacological Evaluation of Antiarrhythmic Drugs.

Motokawa Y, Nakamura Y, Hagiwara-Nagasawa M, Goto A, Chiba K, Lubna NJ, Izumi-Nakaseko H, Ando K, Naito AT, Yamazaki H, Sugiyama A. Motokawa Y, et al. Cardiovasc Toxicol. 2018 Jun;18(3):242-251. doi: 10.1007/s12012-017-9434-y. Cardiovasc Toxicol. 2018. PMID: 29139031

4

Comparison of electropharmacological effects between terfenadine and its active derivative fexofenadine using a cross-over study in halothane-anesthetized dogs to analyze variability of pharmacodynamic and pharmacokinetic profiles of terfenadine and torsadogenic risk of fexofenadine.

Ando K, Nakamura Y, Hagiwara-Nagasawa M, Harada H, Miyamoto H, Inamura N, Takagi K, Goto A, Chiba K, Lubna NJ, Izumi-Nakaseko H, Naito AT, Sugiyama A. Ando K, et al. J Toxicol Sci. 2018;43(3):183-192. doi: 10.2131/jts.43.183. J Toxicol Sci. 2018. PMID: 29540652 Free article.

5

Sunitinib does not acutely alter left ventricular systolic function, but induces diastolic dysfunction.

Wada T, Ando K, Naito AT, Nakamura Y, Goto A, Chiba K, Lubna NJ, Cao X, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Nakazato Y, Sugiyama A. Wada T, et al. Cancer Chemother Pharmacol. 2018 Jul;82(1):65-75. doi: 10.1007/s00280-018-3593-9. Epub 2018 May 2. Cancer Chemother Pharmacol. 2018. PMID: 29721849

6

Analysis of Safety Margin of Lithium Carbonate Against Cardiovascular Adverse Events Assessed in the Halothane-Anesthetized Dogs.

Goto A, Nakamura Y, Lubna NJ, Chiba K, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Ando K, Naito AT, Sugiyama A. Goto A, et al. Cardiovasc Toxicol. 2018 Dec;18(6):530-536. doi: 10.1007/s12012-018-9464-0. Cardiovasc Toxicol. 2018. PMID: 29845450

7

Analysis of torsadogenic and pharmacokinetic profile of E-4031 in dogs bridging the gap of information between in vitro proarrhythmia assay and clinical observation in human subjects.

Goto A, Izumi-Nakaseko H, Hagiwara-Nagasawa M, Chiba K, Ando K, Naito AT, Sugiyama A. Goto A, et al. J Pharmacol Sci. 2018 Jun;137(2):237-240. doi: 10.1016/j.jphs.2018.06.005. Epub 2018 Jun 18. J Pharmacol Sci. 2018. PMID: 29980434 Free article.

8

Electropharmacological effects of intracellular Ca²⁺ handling modulator caldaret on the heart assessed in the halothane-anesthetized dogs.

Sugiyama A, Hagiwara-Nagasawa M, Kambayashi R, Goto A, Chiba K, Ando K, Naito AT, Izumi-Nakaseko H. Sugiyama A, et al. J Pharmacol Sci. 2019 Mar;139(3):180-185. doi: 10.1016/j.jphs.2019.01.004. Epub 2019 Jan 24. J Pharmacol Sci. 2019. PMID: 30738725 Free article.

9

Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors.

Izumi-Nakaseko H, Fujiyoshi M, Hagiwara-Nagasawa M, Goto A, Chiba K, Kambayashi R, Naito AT, Ando K, Kanda Y, Ishii I, Sugiyama A. Izumi-Nakaseko H, et al. Cardiovasc Toxicol. 2020 Feb;20(1):58-70. doi: 10.1007/s12012-019-09538-5. Cardiovasc Toxicol. 2020. PMID: 31280457

10

In vivo characterization of rate-dependent impact on the QT interval of microminipig assessed by atrial electrical pacing: Development of correction formulae of QT interval.

Kambayashi R, Hagiwara-Nagasawa M, Goto A, Chiba K, Izumi-Nakaseko H, Naito AT, Matsumoto A, Sugiyama A. Kambayashi R, et al. J Vet Med Sci. 2019 Dec 18;81(12):1735-1739. doi: 10.1292/jvms.19-0252. Epub 2019 Oct 14. J Vet Med Sci. 2019. PMID: 31611491 Free PMC article.

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