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The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D-erythro-pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine (T-dCyd) and 5-aza-4'-thio-2'-deoxycytidine (aza-T-dCyd) to support clinical development.
Wishka DG, Lopez OD, Rudchenko VF, Huang G, Bahde R, Kumar V, Denysenko SM, Zhang L, Zhang M, Teicher BA, Morris J. Wishka DG, et al. Among authors: huang g. Nucleosides Nucleotides Nucleic Acids. 2021;40(1):68-95. doi: 10.1080/15257770.2020.1832694. Epub 2020 Oct 16. Nucleosides Nucleotides Nucleic Acids. 2021. PMID: 33063584 Free article.
F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd.
Morris J, Wishka DG, Lopez OD, Rudchenko V, Huang G, Hoffman SN, Borgel S, Georgius K, Carter J, Stotler H, Kunkel MW, Collins JM, Hollingshead MG, Teicher BA. Morris J, et al. Among authors: huang g. Mol Cancer Ther. 2021 Apr;20(4):625-631. doi: 10.1158/1535-7163.MCT-20-0738. Mol Cancer Ther. 2021. PMID: 33811149 Free PMC article.
Respiratory syncytial virus vaccine effectiveness among US veterans, September, 2023 to March, 2024: a target trial emulation study.
Bajema KL, Yan L, Li Y, Argraves S, Rajeevan N, Fox A, Vergun R, Berry K, Bui D, Huang Y, Lin HM, Hynes DM, Lucero-Obusan C, Schirmer P, Cunningham F, Huang GD, Aslan M, Ioannou GN. Bajema KL, et al. Among authors: huang gd. Lancet Infect Dis. 2025 Jan 20:S1473-3099(24)00796-5. doi: 10.1016/S1473-3099(24)00796-5. Online ahead of print. Lancet Infect Dis. 2025. PMID: 39848264
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