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Page 1
The nucleus acts as a ruler tailoring cell responses to spatial constraints.
Lomakin AJ, Cattin CJ, Cuvelier D, Alraies Z, Molina M, Nader GPF, Srivastava N, Sáez PJ, Garcia-Arcos JM, Zhitnyak IY, Bhargava A, Driscoll MK, Welf ES, Fiolka R, Petrie RJ, De Silva NS, González-Granado JM, Manel N, Lennon-Duménil AM, Müller DJ, Piel M. Lomakin AJ, et al. Among authors: manel n. Science. 2020 Oct 16;370(6514):eaba2894. doi: 10.1126/science.aba2894. Science. 2020. PMID: 33060332 Free PMC article.
Let me in: Control of HIV nuclear entry at the nuclear envelope.
Bhargava A, Lahaye X, Manel N. Bhargava A, et al. Among authors: manel n. Cytokine Growth Factor Rev. 2018 Apr;40:59-67. doi: 10.1016/j.cytogfr.2018.02.006. Epub 2018 Feb 27. Cytokine Growth Factor Rev. 2018. PMID: 29526438 Review.
The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus.
Gentili M, Lahaye X, Nadalin F, Nader GPF, Puig Lombardi E, Herve S, De Silva NS, Rookhuizen DC, Zueva E, Goudot C, Maurin M, Bochnakian A, Amigorena S, Piel M, Fachinetti D, Londoño-Vallejo A, Manel N. Gentili M, et al. Among authors: manel n. Cell Rep. 2019 Feb 26;26(9):2377-2393.e13. doi: 10.1016/j.celrep.2019.01.105. Cell Rep. 2019. PMID: 30811988 Free PMC article.
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion.
Nader GPF, Agüera-Gonzalez S, Routet F, Gratia M, Maurin M, Cancila V, Cadart C, Palamidessi A, Ramos RN, San Roman M, Gentili M, Yamada A, Williart A, Lodillinsky C, Lagoutte E, Villard C, Viovy JL, Tripodo C, Galon J, Scita G, Manel N, Chavrier P, Piel M. Nader GPF, et al. Among authors: manel n. Cell. 2021 Sep 30;184(20):5230-5246.e22. doi: 10.1016/j.cell.2021.08.035. Epub 2021 Sep 21. Cell. 2021. PMID: 34551315 Free article.
Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages.
De Silva NS, Siewiera J, Alkhoury C, Nader GPF, Nadalin F, de Azevedo K, Couty M, Izquierdo HM, Bhargava A, Conrad C, Maurin M, Antoniadou K, Fouillade C, Londono-Vallejo A, Behrendt R, Bertotti K, Serdjebi C, Lanthiez F, Gallwitz L, Saftig P, Herrero-Fernández B, Saez A, González-Granado JM, van Niel G, Boissonnas A, Piel M, Manel N. De Silva NS, et al. Among authors: manel n. Nat Aging. 2023 Oct;3(10):1251-1268. doi: 10.1038/s43587-023-00488-w. Epub 2023 Sep 18. Nat Aging. 2023. PMID: 37723209
Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes.
Alraies Z, Rivera CA, Delgado MG, Sanséau D, Maurin M, Amadio R, Maria Piperno G, Dunsmore G, Yatim A, Lacerda Mariano L, Kniazeva A, Calmettes V, Sáez PJ, Williart A, Popard H, Gratia M, Lamiable O, Moreau A, Fusilier Z, Crestey L, Albaud B, Legoix P, Dejean AS, Le Dorze AL, Nakano H, Cook DN, Lawrence T, Manel N, Benvenuti F, Ginhoux F, Moreau HD, P F Nader G, Piel M, Lennon-Duménil AM. Alraies Z, et al. Among authors: manel n. Nat Immunol. 2024 Jul;25(7):1193-1206. doi: 10.1038/s41590-024-01856-3. Epub 2024 Jun 4. Nat Immunol. 2024. PMID: 38834865 Free PMC article.
Transmission of innate immune signaling by packaging of cGAMP in viral particles.
Gentili M, Kowal J, Tkach M, Satoh T, Lahaye X, Conrad C, Boyron M, Lombard B, Durand S, Kroemer G, Loew D, Dalod M, Théry C, Manel N. Gentili M, et al. Among authors: manel n. Science. 2015 Sep 11;349(6253):1232-6. doi: 10.1126/science.aab3628. Epub 2015 Jul 30. Science. 2015. PMID: 26229115
86 results