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Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2.
Azouz NP, Klingler AM, Callahan V, Akhrymuk IV, Elez K, Raich L, Henry BM, Benoit JL, Benoit SW, Noé F, Kehn-Hall K, Rothenberg ME. Azouz NP, et al. Among authors: noe f. bioRxiv [Preprint]. 2020 Oct 7:2020.05.04.077826. doi: 10.1101/2020.05.04.077826. bioRxiv. 2020. Update in: Pathog Immun. 2021 Apr 26;6(1):55-74. doi: 10.20411/pai.v6i1.408 PMID: 33052338 Free PMC article. Updated. Preprint.
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Sheltzer JM, Kjolby M, Pöhlmann S. Hoffmann M, et al. Among authors: noe f. bioRxiv [Preprint]. 2020 Aug 5:2020.08.05.237651. doi: 10.1101/2020.08.05.237651. bioRxiv. 2020. Update in: EBioMedicine. 2021 Mar;65:103255. doi: 10.1016/j.ebiom.2021.103255 PMID: 32793911 Free PMC article. Updated. Preprint.
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Arora P, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Danov O, Jonigk D, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Kjolby M, Braun A, Sheltzer JM, Pöhlmann S. Hoffmann M, et al. Among authors: noe f. EBioMedicine. 2021 Mar;65:103255. doi: 10.1016/j.ebiom.2021.103255. Epub 2021 Mar 4. EBioMedicine. 2021. PMID: 33676899 Free PMC article.
Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2.
Azouz NP, Klingler AM, Callahan V, Akhrymuk IV, Elez K, Raich L, Henry BM, Benoit JL, Benoit SW, Noé F, Kehn-Hall K, Rothenberg ME. Azouz NP, et al. Among authors: noe f. Pathog Immun. 2021 Apr 26;6(1):55-74. doi: 10.20411/pai.v6i1.408. eCollection 2021. Pathog Immun. 2021. PMID: 33969249 Free PMC article.
Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties.
Hempel T, Elez K, Krüger N, Raich L, Shrimp JH, Danov O, Jonigk D, Braun A, Shen M, Hall MD, Pöhlmann S, Hoffmann M, Noé F. Hempel T, et al. Among authors: noe f. Chem Sci. 2021 Aug 26;12(38):12600-12609. doi: 10.1039/d1sc01494c. eCollection 2021 Oct 6. Chem Sci. 2021. PMID: 34703545 Free PMC article.
Discovery of a hidden transient state in all bromodomain families.
Raich L, Meier K, Günther J, Christ CD, Noé F, Olsson S. Raich L, et al. Among authors: noe f. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2017427118. doi: 10.1073/pnas.2017427118. Proc Natl Acad Sci U S A. 2021. PMID: 33468647 Free PMC article.
Sub-membrane actin rings compartmentalize the plasma membrane.
Rentsch J, Bandstra S, Sezen B, Sigrist P, Bottanelli F, Schmerl B, Shoichet S, Noé F, Sadeghi M, Ewers H. Rentsch J, et al. Among authors: noe f. J Cell Biol. 2024 Apr 1;223(4):e202310138. doi: 10.1083/jcb.202310138. Epub 2024 Jan 22. J Cell Biol. 2024. PMID: 38252080 Free PMC article.
311 results