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Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands.
Cerda-Cavieres C, Quiroz G, Iturriaga-Vásquez P, Rodríguez-Lavado J, Alarcón-Espósito J, Saitz C, Pessoa-Mahana CD, Chung H, Araya-Maturana R, Mella-Raipán J, Cabezas D, Ojeda-Gómez C, Reyes-Parada M, Pessoa-Mahana H. Cerda-Cavieres C, et al. Among authors: iturriaga vasquez p. Molecules. 2020 Oct 10;25(20):4614. doi: 10.3390/molecules25204614. Molecules. 2020. PMID: 33050524 Free PMC article.
4-Methylthioamphetamine increases dopamine in the rat striatum and has rewarding effects in vivo.
Sotomayor-Zárate R, Quiroz G, Araya KA, Abarca J, Ibáñez MR, Montecinos A, Guajardo C, Núñez G, Fierro A, Moya PR, Iturriaga-Vásquez P, Gómez-Molina C, Gysling K, Reyes-Parada M. Sotomayor-Zárate R, et al. Basic Clin Pharmacol Toxicol. 2012 Dec;111(6):371-9. doi: 10.1111/j.1742-7843.2012.00926.x. Epub 2012 Aug 31. Basic Clin Pharmacol Toxicol. 2012. PMID: 22788961 Free article.
Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor.
Pessoa-Mahana H, González-Lira C, Fierro A, Zapata-Torres G, Pessoa-Mahana CD, Ortiz-Severin J, Iturriaga-Vásquez P, Reyes-Parada M, Silva-Matus P, Saitz-Barría C, Araya-Maturana R. Pessoa-Mahana H, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7604-11. doi: 10.1016/j.bmc.2013.10.036. Epub 2013 Nov 6. Bioorg Med Chem. 2013. PMID: 24262884
Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction.
Sotomayor-Zárate R, Jara P, Araos P, Vinet R, Quiroz G, Renard GM, Espinosa P, Hurtado-Guzmán C, Moya PR, Iturriaga-Vásquez P, Gysling K, Reyes-Parada M. Sotomayor-Zárate R, et al. Basic Clin Pharmacol Toxicol. 2014 May;114(5):395-9. doi: 10.1111/bcpt.12168. Epub 2013 Dec 7. Basic Clin Pharmacol Toxicol. 2014. PMID: 24314229 Free article.
44 results