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Sarcoma treatment in the era of molecular medicine.
Grünewald TG, Alonso M, Avnet S, Banito A, Burdach S, Cidre-Aranaz F, Di Pompo G, Distel M, Dorado-Garcia H, Garcia-Castro J, González-González L, Grigoriadis AE, Kasan M, Koelsche C, Krumbholz M, Lecanda F, Lemma S, Longo DL, Madrigal-Esquivel C, Morales-Molina Á, Musa J, Ohmura S, Ory B, Pereira-Silva M, Perut F, Rodriguez R, Seeling C, Al Shaaili N, Shaabani S, Shiavone K, Sinha S, Tomazou EM, Trautmann M, Vela M, Versleijen-Jonkers YM, Visgauss J, Zalacain M, Schober SJ, Lissat A, English WR, Baldini N, Heymann D. Grünewald TG, et al. Among authors: rodriguez r. EMBO Mol Med. 2020 Nov 6;12(11):e11131. doi: 10.15252/emmm.201911131. Epub 2020 Oct 13. EMBO Mol Med. 2020. PMID: 33047515 Free PMC article. Review.
Bone microenvironment signals in osteosarcoma development.
Alfranca A, Martinez-Cruzado L, Tornin J, Abarrategi A, Amaral T, de Alava E, Menendez P, Garcia-Castro J, Rodriguez R. Alfranca A, et al. Among authors: rodriguez r. Cell Mol Life Sci. 2015 Aug;72(16):3097-113. doi: 10.1007/s00018-015-1918-y. Epub 2015 May 3. Cell Mol Life Sci. 2015. PMID: 25935149 Free PMC article. Review.
Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies.
Abarrategi A, Tornin J, Martinez-Cruzado L, Hamilton A, Martinez-Campos E, Rodrigo JP, González MV, Baldini N, Garcia-Castro J, Rodriguez R. Abarrategi A, et al. Among authors: rodriguez r. Stem Cells Int. 2016;2016:3631764. doi: 10.1155/2016/3631764. Epub 2016 Jun 5. Stem Cells Int. 2016. PMID: 27366153 Free PMC article. Review.
SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications.
Menendez ST, Rey V, Martinez-Cruzado L, Gonzalez MV, Morales-Molina A, Santos L, Blanco V, Alvarez C, Estupiñan O, Allonca E, Rodrigo JP, García-Castro J, Garcia-Pedrero JM, Rodriguez R. Menendez ST, et al. Among authors: rodriguez r. Cancers (Basel). 2020 Apr 13;12(4):964. doi: 10.3390/cancers12040964. Cancers (Basel). 2020. PMID: 32295077 Free PMC article.
GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-β.
Carrillo-Gálvez AB, Quintero JE, Rodríguez R, Menéndez ST, Victoria González M, Blanco-Lorenzo V, Allonca E, de Araújo Farias V, González-Correa JE, Erill-Sagalés N, Martínez-Zubiaurre I, Hellevik T, Sánchez-Hernández S, Muñoz P, Zurita F, Martín F, Rodríguez-Manzaneque JC, Anderson P. Carrillo-Gálvez AB, et al. Among authors: rodriguez r, rodriguez manzaneque jc. Cell Death Dis. 2020 Nov 17;11(11):985. doi: 10.1038/s41419-020-03197-z. Cell Death Dis. 2020. PMID: 33203838 Free PMC article.
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma.
Rey V, Tornín J, Alba-Linares JJ, Robledo C, Murillo D, Rodríguez A, Gallego B, Huergo C, Viera C, Braña A, Astudillo A, Heymann D, Szuhai K, Bovée JVMG, Fernández AF, Fraga MF, Alonso J, Rodríguez R. Rey V, et al. Among authors: rodriguez a, rodriguez r. EBioMedicine. 2024 Apr;102:105090. doi: 10.1016/j.ebiom.2024.105090. Epub 2024 Mar 27. EBioMedicine. 2024. PMID: 38547578 Free PMC article.
4,379 results