Du C - Search Results

1

Optimization and kinetic modeling of interchain disulfide bond reoxidation of monoclonal antibodies in bioprocesses.

Tang P, Tan Z, Ehamparanathan V, Ren T, Hoffman L, Du C, Song Y, Tao L, Lewandowski A, Ghose S, Li ZJ, Liu S. Tang P, et al. Among authors: du c. MAbs. 2020 Jan-Dec;12(1):1829336. doi: 10.1080/19420862.2020.1829336. MAbs. 2020. PMID: 33031716 Free PMC article.

2

Using hydrogen peroxide to prevent antibody disulfide bond reduction during manufacturing process.

Du C, Huang Y, Borwankar A, Tan Z, Cura A, Yee JC, Singh N, Ludwig R, Borys M, Ghose S, Mussa N, Li ZJ. Du C, et al. MAbs. 2018 Apr;10(3):500-510. doi: 10.1080/19420862.2018.1424609. Epub 2018 Jan 23. MAbs. 2018. PMID: 29336721 Free PMC article.

3

On-column disulfide bond formation of monoclonal antibodies during Protein A chromatography eliminates low molecular weight species and rescues reduced antibodies.

Tan Z, Ehamparanathan V, Ren T, Tang P, Hoffman L, Kuang J, Liu P, Huang C, Du C, Tao L, Chemmalil L, Lewandowski A, Ghose S, Li ZJ, Liu S. Tan Z, et al. Among authors: du c. MAbs. 2020 Jan-Dec;12(1):1829333. doi: 10.1080/19420862.2020.1829333. MAbs. 2020. PMID: 33016217 Free PMC article.

4

Vitamin B₁₂ association with mAbs: Mechanism and potential mitigation strategies.

Du C, Martin R, Huang Y, Borwankar A, Tan Z, West J, Singh N, Borys M, Ghose S, Ludwig R, Tao L, Li ZJ. Du C, et al. Biotechnol Bioeng. 2018 Apr;115(4):900-909. doi: 10.1002/bit.26511. Epub 2017 Dec 19. Biotechnol Bioeng. 2018. PMID: 29205285

5

Strategies for high-concentration drug substance manufacturing to facilitate subcutaneous administration: A review.

Holstein M, Hung J, Feroz H, Ranjan S, Du C, Ghose S, Li ZJ. Holstein M, et al. Among authors: du c. Biotechnol Bioeng. 2020 Nov;117(11):3591-3606. doi: 10.1002/bit.27510. Epub 2020 Aug 3. Biotechnol Bioeng. 2020. PMID: 32687221 Review.

6

Protection of therapeutic antibodies from visible light induced degradation: Use safe light in manufacturing and storage.

Du C, Barnett G, Borwankar A, Lewandowski A, Singh N, Ghose S, Borys M, Li ZJ. Du C, et al. Eur J Pharm Biopharm. 2018 Jun;127:37-43. doi: 10.1016/j.ejpb.2018.02.007. Epub 2018 Feb 7. Eur J Pharm Biopharm. 2018. PMID: 29427628

7

A Nondestructive Method for Measuring Protein Distribution in Frozen Drug Substance.

Du C, Borwankar A, Singh N, Borys M, Li ZJ. Du C, et al. J Pharm Sci. 2017 Aug;106(8):1978-1986. doi: 10.1016/j.xphs.2017.04.047. Epub 2017 May 5. J Pharm Sci. 2017. PMID: 28483421

8

PLGA Conical Nail Fixation for Acetabular Chondrolabral Delamination in Femoroacetabular Impingement Promotes Cartilage and Labrum Regeneration in a Porcine Model.

Du C, Gao G, Zhu Y, Zhang S, Zhang Y, Wang J, Liu Z, Xu Y. Du C, et al. Am J Sports Med. 2025 Jan;53(1):90-103. doi: 10.1177/03635465241299414. Am J Sports Med. 2025. PMID: 39741490

9

Clickable liposomes for on-demand reversal of antiplatelet drugs: Towards a safe management of bleeding risks associated with antithrombotic therapy.

Cheng X, Wang C, Xu J, Huang Y, Chen Z, Zhong L, Du C, Nie G, Zhang Y. Cheng X, et al. Among authors: du c. J Control Release. 2024 Dec 29:S0168-3659(24)00925-8. doi: 10.1016/j.jconrel.2024.12.070. Online ahead of print. J Control Release. 2024. PMID: 39740697

10

Differential effects of fine particulate matter constituents on acute coronary syndrome onset.

Jiang Y, Du C, Chen R, Hu J, Zhu X, Xue X, He Q, Lu J, Ge J, Huo Y, Kan H. Jiang Y, et al. Among authors: du c. Nat Commun. 2024 Dec 30;15(1):10848. doi: 10.1038/s41467-024-55080-6. Nat Commun. 2024. PMID: 39737969 Free PMC article.

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