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Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.
Colclough N, Chen K, Johnström P, Strittmatter N, Yan Y, Wrigley GL, Schou M, Goodwin R, Varnäs K, Adua SJ, Zhao M, Nguyen DX, Maglennon G, Barton P, Atkinson J, Zhang L, Janefeldt A, Wilson J, Smith A, Takano A, Arakawa R, Kondrashov M, Malmquist J, Revunov E, Vazquez-Romero A, Moein MM, Windhorst AD, Karp NA, Finlay MRV, Ward RA, Yates JWT, Smith PD, Farde L, Cheng Z, Cross DAE. Colclough N, et al. Among authors: vazquez romero a. Clin Cancer Res. 2021 Jan 1;27(1):189-201. doi: 10.1158/1078-0432.CCR-19-1871. Epub 2020 Oct 7. Clin Cancer Res. 2021. PMID: 33028591
A PET study in healthy subjects of brain exposure of 11C-labelled osimertinib - A drug intended for treatment of brain metastases in non-small cell lung cancer.
Varrone A, Varnäs K, Jucaite A, Cselényi Z, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Halldin C, Brown AP, Vishwanathan K, Farde L. Varrone A, et al. Among authors: vazquez romero a. J Cereb Blood Flow Metab. 2020 Apr;40(4):799-807. doi: 10.1177/0271678X19843776. Epub 2019 Apr 20. J Cereb Blood Flow Metab. 2020. PMID: 31006308 Free PMC article.
Synthesis and Preclinical Evaluation of 6-[18F]Fluorine-α-methyl-l-tryptophan, a Novel PET Tracer for Measuring Tryptophan Uptake.
Krasikova R, Kondrashov M, Avagliano C, Petukhov M, Vazquez-Romero A, Revunov E, Johnström P, Tari L, Tóth M, Häggkvist J, Erhardt S, Cervenka S, Schou M. Krasikova R, et al. Among authors: vazquez romero a. ACS Chem Neurosci. 2020 Jun 17;11(12):1756-1761. doi: 10.1021/acschemneuro.0c00135. Epub 2020 Jun 5. ACS Chem Neurosci. 2020. PMID: 32343551
Brain exposure of the ATM inhibitor AZD1390 in humans-a positron emission tomography study.
Jucaite A, Stenkrona P, Cselényi Z, De Vita S, Buil-Bruna N, Varnäs K, Savage A, Varrone A, Johnström P, Schou M, Davison C, Sykes A, Pilla Reddy V, Hoch M, Vazquez-Romero A, Moein MM, Halldin C, Merchant MS, Pass M, Farde L. Jucaite A, et al. Among authors: vazquez romero a. Neuro Oncol. 2021 Apr 12;23(4):687-696. doi: 10.1093/neuonc/noaa238. Neuro Oncol. 2021. PMID: 33123736 Free PMC article. Clinical Trial.
Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung - a test-retest PET study in control subjects.
Cselényi Z, Jucaite A, Kristensson C, Stenkrona P, Ewing P, Varrone A, Johnström P, Schou M, Vazquez-Romero A, Moein MM, Bolin M, Siikanen J, Grybäck P, Larsson B, Halldin C, Grime K, Eriksson UG, Farde L. Cselényi Z, et al. Among authors: vazquez romero a. EJNMMI Res. 2020 Jun 3;10(1):59. doi: 10.1186/s13550-020-00634-0. EJNMMI Res. 2020. PMID: 32495011 Free PMC article.
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