Ottone OK - Search Results

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Sox9 deletion causes severe intervertebral disc degeneration characterized by apoptosis, matrix remodeling, and compartment-specific transcriptomic changes.

Tsingas M, Ottone OK, Haseeb A, Barve RA, Shapiro IM, Lefebvre V, Risbud MV. Tsingas M, et al. Among authors: ottone ok. Matrix Biol. 2020 Dec;94:110-133. doi: 10.1016/j.matbio.2020.09.003. Epub 2020 Oct 4. Matrix Biol. 2020. PMID: 33027692 Free PMC article.

TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression.

Tessier S, Tran VA, Ottone OK, Novais EJ, Doolittle A, DiMuzio MJ, Shapiro IM, Risbud MV. Tessier S, et al. Among authors: ottone ok. Matrix Biol. 2020 May;87:94-111. doi: 10.1016/j.matbio.2019.10.007. Epub 2019 Nov 9. Matrix Biol. 2020. PMID: 31707045 Free PMC article.

Differential Effect of Long-Term Systemic Exposure of TNFα on Health of the Annulus Fibrosus and Nucleus Pulposus of the Intervertebral Disc.

Gorth DJ, Ottone OK, Shapiro IM, Risbud MV. Gorth DJ, et al. Among authors: ottone ok. J Bone Miner Res. 2020 Apr;35(4):725-737. doi: 10.1002/jbmr.3931. Epub 2020 Jan 6. J Bone Miner Res. 2020. PMID: 31800975 Free PMC article.

The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration.

Ottone OK, Kim CJ, Collins JA, Risbud MV. Ottone OK, et al. Front Immunol. 2022 Jun 13;13:882407. doi: 10.3389/fimmu.2022.882407. eCollection 2022. Front Immunol. 2022. PMID: 35769461 Free PMC article.

Corrigendum: The cGAS-STING pathway affects vertebral bone but does not promote intervertebral disc cell senescence or degeneration.

Ottone OK, Kim CJ, Collins JA, Risbud MV. Ottone OK, et al. Front Immunol. 2023 Apr 26;14:1201655. doi: 10.3389/fimmu.2023.1201655. eCollection 2023. Front Immunol. 2023. PMID: 37180136 Free PMC article.

Oral citrate supplementation mitigates age-associated pathological intervertebral disc calcification in LG/J mice.

Ottone OK, Mundo JJ, Kwakye BN, Slaweski A, Collins JA, Wu Q, Connelly MA, Niaziorimi F, van de Wetering K, Risbud MV. Ottone OK, et al. bioRxiv [Preprint]. 2024 Jul 19:2024.07.17.604008. doi: 10.1101/2024.07.17.604008. bioRxiv. 2024. PMID: 39071393 Free PMC article. Preprint.

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