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Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels.
Shi J, Hyman AJ, De Vecchis D, Chong J, Lichtenstein L, Futers TS, Rouahi M, Salvayre AN, Auge N, Kalli AC, Beech DJ. Shi J, et al. Among authors: auge n. Cell Rep. 2020 Oct 6;33(1):108225. doi: 10.1016/j.celrep.2020.108225. Cell Rep. 2020. PMID: 33027663 Free PMC article.
nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe-/- Mice.
Lallemand T, Rouahi M, Swiader A, Grazide MH, Geoffre N, Alayrac P, Recazens E, Coste A, Salvayre R, Nègre-Salvayre A, Augé N. Lallemand T, et al. Among authors: auge n. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1479-1492. doi: 10.1161/ATVBAHA.118.311208. Epub 2018 May 24. Arterioscler Thromb Vasc Biol. 2018. PMID: 29794115 Free PMC article.
The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation.
Augé N, Andrieu N, Nègre-Salvayre A, Thiers JC, Levade T, Salvayre R. Augé N, et al. J Biol Chem. 1996 Aug 9;271(32):19251-5. doi: 10.1074/jbc.271.32.19251. J Biol Chem. 1996. PMID: 8702606 Free article.
Our laboratory previously demonstrated that the growth of bovine aortic SMC was stimulated by mildly oxidized low density lipoproteins (oxLDL) and that the mitogenic effect of oxLDL was greater than that induced by native LDL (Auge, N., Pieraggi, M. T., Thiers, J. C …
Our laboratory previously demonstrated that the growth of bovine aortic SMC was stimulated by mildly oxidized low density lipoproteins (oxLD …
Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase.
Augé N, Nikolova-Karakashian M, Carpentier S, Parthasarathy S, Nègre-Salvayre A, Salvayre R, Merrill AH Jr, Levade T. Augé N, et al. J Biol Chem. 1999 Jul 30;274(31):21533-8. doi: 10.1074/jbc.274.31.21533. J Biol Chem. 1999. PMID: 10419457 Free article.
We previously demonstrated that the proliferation of cultured vascular smooth muscle cells (SMC) induced by oxLDL is preceded by an increase in neutral sphingomyelinase activity, sphingomyelin turnover to ceramide, and stimulation of mitogen-activated protein kinases (Auge
We previously demonstrated that the proliferation of cultured vascular smooth muscle cells (SMC) induced by oxLDL is preceded by an increase …
60 results