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Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis.
Cai Z, Li CF, Han F, Liu C, Zhang A, Hsu CC, Peng D, Zhang X, Jin G, Rezaeian AH, Wang G, Zhang W, Pan BS, Wang CY, Wang YH, Wu SY, Yang SC, Hsu FC, D'Agostino RB Jr, Furdui CM, Kucera GL, Parks JS, Chilton FH, Huang CY, Tsai FJ, Pasche B, Watabe K, Lin HK. Cai Z, et al. Mol Cell. 2020 Oct 15;80(2):263-278.e7. doi: 10.1016/j.molcel.2020.09.018. Epub 2020 Oct 5. Mol Cell. 2020. PMID: 33022274 Free PMC article.
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.
Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, Lin E, Ketkar A, Eoff R, Xu ZG, Chen ZZ, Li HY, Lin HK. Hsu CC, et al. Among authors: cai z. Mol Cell. 2021 Sep 16;81(18):3803-3819.e7. doi: 10.1016/j.molcel.2021.08.025. Mol Cell. 2021. PMID: 34547240 Free PMC article.
SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling.
Xu C, Jin G, Wu H, Cui W, Wang YH, Manne RK, Wang G, Zhang W, Zhang X, Han F, Cai Z, Pan BS, Hsu CC, Liu Y, Zhang A, Long J, Zou H, Wang S, Ma X, Duan J, Wang B, Liu W, Lan H, Xiong Q, Xue G, Chen Z, Xu Z, Furth ME, Haigh Molina S, Lu Y, Xie D, Bian XW, Lin HK. Xu C, et al. Among authors: cai z. J Clin Invest. 2022 Mar 1;132(5):e141797. doi: 10.1172/JCI141797. J Clin Invest. 2022. PMID: 35229723 Free PMC article.
Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
Jin G, Lee SW, Zhang X, Cai Z, Gao Y, Chou PC, Rezaeian AH, Han F, Wang CY, Yao JC, Gong Z, Chan CH, Huang CY, Tsai FJ, Tsai CH, Tu SH, Wu CH, Sarbassov dos D, Ho YS, Lin HK. Jin G, et al. Among authors: cai z. Mol Cell. 2015 Jun 18;58(6):989-1000. doi: 10.1016/j.molcel.2015.05.010. Epub 2015 Jun 4. Mol Cell. 2015. PMID: 26051179 Free PMC article.
9,177 results