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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium.
Jacob F, Pather SR, Huang WK, Zhang F, Wong SZH, Zhou H, Cubitt B, Fan W, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, Carlos de la Torre J, Ming GL. Jacob F, et al. Among authors: chen cz. Cell Stem Cell. 2020 Dec 3;27(6):937-950.e9. doi: 10.1016/j.stem.2020.09.016. Epub 2020 Sep 21. Cell Stem Cell. 2020. PMID: 33010822 Free PMC article.
Advancing precision medicine with personalized drug screening.
Gorshkov K, Chen CZ, Marshall RE, Mihatov N, Choi Y, Nguyen DT, Southall N, Chen KG, Park JK, Zheng W. Gorshkov K, et al. Among authors: chen cz, chen kg. Drug Discov Today. 2019 Jan;24(1):272-278. doi: 10.1016/j.drudis.2018.08.010. Epub 2018 Aug 17. Drug Discov Today. 2019. PMID: 30125678 Free PMC article. Review.
The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Xu M, Pradhan M, Tran BN, Zhu W, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Simeonov A, Michael S, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: chen cz. bioRxiv [Preprint]. 2020 May 28:2020.05.16.091520. doi: 10.1101/2020.05.16.091520. bioRxiv. 2020. Update in: ACS Infect Dis. 2021 Jun 11;7(6):1389-1408. doi: 10.1021/acsinfecdis.0c00349 PMID: 32511355 Free PMC article. Updated. Preprint.
419 results