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Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.
Darwich NF, Phan JM, Kim B, Suh E, Papatriantafyllou JD, Changolkar L, Nguyen AT, O'Rourke CM, He Z, Porta S, Gibbons GS, Luk KC, Papageorgiou SG, Grossman M, Massimo L, Irwin DJ, McMillan CT, Nasrallah IM, Toro C, Aguirre GK, Van Deerlin VM, Lee EB. Darwich NF, et al. Among authors: kim b. Science. 2020 Nov 20;370(6519):eaay8826. doi: 10.1126/science.aay8826. Epub 2020 Oct 1. Science. 2020. PMID: 33004675 Free PMC article.
Tau immunotherapy is associated with glial responses in FTLD-tau.
Kim B, Mikytuck B, Suh E, Gibbons GS, Van Deerlin VM, Vaishnavi SN, Spindler MA, Massimo L, Grossman M, Trojanowski JQ, Irwin DJ, Lee EB. Kim B, et al. Acta Neuropathol. 2021 Aug;142(2):243-257. doi: 10.1007/s00401-021-02318-y. Epub 2021 May 5. Acta Neuropathol. 2021. PMID: 33950293 Free PMC article.
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway.
Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA. Lin YC, et al. Among authors: kim b. Nat Neurosci. 2021 Aug;24(8):1077-1088. doi: 10.1038/s41593-021-00859-9. Epub 2021 May 31. Nat Neurosci. 2021. PMID: 34059832 Free PMC article.
TREM2 risk variants are associated with atypical Alzheimer's disease.
Kim B, Suh E, Nguyen AT, Prokop S, Mikytuck B, Olatunji OA, Robinson JL, Grossman M, Phillips JS, Irwin DJ, Mechanic-Hamilton D, Wolk DA, Trojanowski JQ, McMillan CT, Van Deerlin VM, Lee EB. Kim B, et al. Acta Neuropathol. 2022 Dec;144(6):1085-1102. doi: 10.1007/s00401-022-02495-4. Epub 2022 Sep 16. Acta Neuropathol. 2022. PMID: 36112222 Free PMC article.
Association of quantitative histopathology measurements with antemortem medial temporal lobe cortical thickness in the Alzheimer's disease continuum.
Denning AE, Ittyerah R, Levorse LM, Sadeghpour N, Athalye C, Chung E, Ravikumar S, Dong M, Duong MT, Li Y, Ilesanmi A, Sreepada LP, Sabatini P, Lowe M, Bahena A, Zablah J, Spencer BE, Watanabe R, Kim B, Sørensen MH, Khandelwal P, Brown C, Hrybouski S, Xie SX, de Flores R, Robinson JL, Schuck T, Ohm DT, Arezoumandan S, Porta S, Detre JA, Insausti R, Wisse LEM, Das SR, Irwin DJ, Lee EB, Wolk DA, Yushkevich PA. Denning AE, et al. Among authors: kim b. Acta Neuropathol. 2024 Sep 3;148(1):37. doi: 10.1007/s00401-024-02789-9. Acta Neuropathol. 2024. PMID: 39227502 Free PMC article.
Clinical Manifestations.
Kim BR, Park KH, Jeong JH, Kim GH. Kim BR, et al. Alzheimers Dement. 2024 Dec;20 Suppl 3:e088134. doi: 10.1002/alz.088134. Alzheimers Dement. 2024. PMID: 39750300
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