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Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model.
Amanat F, Strohmeier S, Rathnasinghe R, Schotsaert M, Coughlan L, García-Sastre A, Krammer F. Amanat F, et al. Among authors: krammer f. bioRxiv [Preprint]. 2020 Sep 17:2020.09.16.300970. doi: 10.1101/2020.09.16.300970. bioRxiv. 2020. Update in: mBio. 2021 Mar 2;12(2):e02648-20. doi: 10.1128/mBio.02648-20 PMID: 32995785 Free PMC article. Updated. Preprint.
Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses.
Pica N, Hai R, Krammer F, Wang TT, Maamary J, Eggink D, Tan GS, Krause JC, Moran T, Stein CR, Banach D, Wrammert J, Belshe RB, García-Sastre A, Palese P. Pica N, et al. Among authors: krammer f. Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2573-8. doi: 10.1073/pnas.1200039109. Epub 2012 Jan 30. Proc Natl Acad Sci U S A. 2012. PMID: 22308500 Free PMC article.
566 results