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Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801.
Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, Gully K, Askin F, Browne E, Jones C, Pickles R, Baric R, Garcia JV. Wahl A, et al. Res Sq [Preprint]. 2020 Sep 24:rs.3.rs-80404. doi: 10.21203/rs.3.rs-80404/v1. Res Sq. 2020. Update in: Nature. 2021 Mar;591(7850):451-457. doi: 10.1038/s41586-021-03312-w PMID: 32995766 Free PMC article. Updated. Preprint.
Cryptopatches are essential for the development of human GALT.
Nochi T, Denton PW, Wahl A, Garcia JV. Nochi T, et al. Among authors: wahl a. Cell Rep. 2013 Jun 27;3(6):1874-84. doi: 10.1016/j.celrep.2013.05.037. Epub 2013 Jun 20. Cell Rep. 2013. PMID: 23791525 Free PMC article.
Precision mouse models with expanded tropism for human pathogens.
Wahl A, De C, Abad Fernandez M, Lenarcic EM, Xu Y, Cockrell AS, Cleary RA, Johnson CE, Schramm NJ, Rank LM, Newsome IG, Vincent HA, Sanders W, Aguilera-Sandoval CR, Boone A, Hildebrand WH, Dayton PA, Baric RS, Pickles RJ, Braunstein M, Moorman NJ, Goonetilleke N, Victor Garcia J. Wahl A, et al. Nat Biotechnol. 2019 Oct;37(10):1163-1173. doi: 10.1038/s41587-019-0225-9. Epub 2019 Aug 26. Nat Biotechnol. 2019. PMID: 31451733 Free PMC article.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH 3rd, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, Grant PO, Bluemling GR, Kolykhalov AA, Natchus MG, Askin FB, Painter G, Browne EP, Jones CD, Pickles RJ, Baric RS, Garcia JV. Wahl A, et al. Nature. 2021 Mar;591(7850):451-457. doi: 10.1038/s41586-021-03312-w. Epub 2021 Feb 9. Nature. 2021. PMID: 33561864 Free PMC article.
Human T cells efficiently control RSV infection.
De C, Pickles RJ, Yao W, Liao B, Boone A, Choi M, Battaglia DM, Askin FB, Whitmire JK, Silvestri G, Garcia JV, Wahl A. De C, et al. Among authors: wahl a. JCI Insight. 2023 Jun 8;8(11):e168110. doi: 10.1172/jci.insight.168110. JCI Insight. 2023. PMID: 37159271 Free PMC article.
605 results