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103 results

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Page 1
Canagliflozin extends life span in genetically heterogeneous male but not female mice.
Miller RA, Harrison DE, Allison DB, Bogue M, Debarba L, Diaz V, Fernandez E, Galecki A, Garvey WT, Jayarathne H, Kumar N, Javors MA, Ladiges WC, Macchiarini F, Nelson J, Reifsnyder P, Rosenthal NA, Sadagurski M, Salmon AB, Smith DL Jr, Snyder JM, Lombard DB, Strong R. Miller RA, et al. Among authors: lombard db. JCI Insight. 2020 Nov 5;5(21):e140019. doi: 10.1172/jci.insight.140019. JCI Insight. 2020. PMID: 32990681 Free PMC article.
Ageing: Sorting out the sirtuins.
Lombard DB, Miller RA. Lombard DB, et al. Nature. 2012 Mar 7;483(7388):166-7. doi: 10.1038/nature10950. Nature. 2012. PMID: 22367538 No abstract available.
Canagliflozin Increases Intestinal Adenoma Burden in Female ApcMin/+ Mice.
Korfhage J, Skinner ME, Basu J, Greenson JK, Miller RA, Lombard DB. Korfhage J, et al. Among authors: lombard db. J Gerontol A Biol Sci Med Sci. 2022 Feb 3;77(2):215-220. doi: 10.1093/gerona/glab254. J Gerontol A Biol Sci Med Sci. 2022. PMID: 34448851 Free PMC article.
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice.
Strong R, Miller RA, Cheng CJ, Nelson JF, Gelfond J, Allani SK, Diaz V, Dorigatti AO, Dorigatti J, Fernandez E, Galecki A, Ginsburg B, Hamilton KL, Javors MA, Kornfeld K, Kaeberlein M, Kumar S, Lombard DB, Lopez-Cruzan M, Miller BF, Rabinovitch P, Reifsnyder P, Rosenthal NA, Bogue MA, Salmon AB, Suh Y, Verdin E, Weissbach H, Newman J, Maccchiarini F, Harrison DE. Strong R, et al. Among authors: lombard db. Aging Cell. 2022 Dec;21(12):e13724. doi: 10.1111/acel.13724. Epub 2022 Sep 30. Aging Cell. 2022. PMID: 36179270 Free PMC article.
Ageing: longevity hits a roadblock.
Lombard DB, Pletcher SD, Cantó C, Auwerx J. Lombard DB, et al. Nature. 2011 Sep 21;477(7365):410-1. doi: 10.1038/477410a. Nature. 2011. PMID: 21938058 No abstract available.
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, MacDonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R. Sebastián C, et al. Among authors: lombard db. Cell. 2012 Dec 7;151(6):1185-99. doi: 10.1016/j.cell.2012.10.047. Cell. 2012. PMID: 23217706 Free PMC article.
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Park J, et al. Among authors: lombard db. Mol Cell. 2013 Jun 27;50(6):919-30. doi: 10.1016/j.molcel.2013.06.001. Mol Cell. 2013. PMID: 23806337 Free PMC article.
103 results