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Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study.
Galea J, Ogungbenro K, Hulme S, Greenhalgh A, Aarons L, Scarth S, Hutchinson P, Grainger S, King A, Hopkins SJ, Rothwell N, Tyrrell P. Galea J, et al. J Cereb Blood Flow Metab. 2011 Feb;31(2):439-47. doi: 10.1038/jcbfm.2010.103. Epub 2010 Jul 14. J Cereb Blood Flow Metab. 2011. PMID: 20628399 Free PMC article.
The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial.
Singh N, Hopkins SJ, Hulme S, Galea JP, Hoadley M, Vail A, Hutchinson PJ, Grainger S, Rothwell NJ, King AT, Tyrrell PJ. Singh N, et al. Among authors: galea jp. J Neuroinflammation. 2014 Jan 3;11:1. doi: 10.1186/1742-2094-11-1. J Neuroinflammation. 2014. PMID: 24383930 Free PMC article. Clinical Trial.
Impact of specialist neurovascular care in subarachnoid haemorrhage.
Khan AU, Dulhanty L, Vail A, Tyrrell P, Galea J, Patel HC. Khan AU, et al. Among authors: galea j. Clin Neurol Neurosurg. 2015 Jun;133:55-60. doi: 10.1016/j.clineuro.2015.03.006. Epub 2015 Mar 16. Clin Neurol Neurosurg. 2015. PMID: 25839916
317 results