Selective incorporation of polyanionic molecules into hamster prions.
Geoghegan JC, Valdes PA, Orem NR, Deleault NR, Williamson RA, Harris BT, Supattapone S.
Geoghegan JC, et al. Among authors: supattapone s.
J Biol Chem. 2007 Dec 14;282(50):36341-53. doi: 10.1074/jbc.M704447200. Epub 2007 Oct 16.
J Biol Chem. 2007.
PMID: 17940287
Free PMC article.
We previously showed that the protein misfolding cyclic amplification (PMCA) technique can be used to form infectious prion molecules de novo from purified native PrPC molecules in an autocatalytic process requiring accessory polyanions (Deleault, N. R., Harris, B. T., Rees, J. R …
We previously showed that the protein misfolding cyclic amplification (PMCA) technique can be used to form infectious prion molecules de nov …