Alexiou P - Search Results

1

Discovery of Small-Molecule Inhibitors of Receptor Activator of Nuclear Factor-κB Ligand with a Superior Therapeutic Index.

Rinotas V, Papakyriakou A, Violitzi F, Papaneophytou C, Ouzouni MD, Alexiou P, Strongilos A, Couladouros E, Kontopidis G, Eliopoulos E, Douni E. Rinotas V, et al. Among authors: alexiou p. J Med Chem. 2020 Oct 22;63(20):12043-12059. doi: 10.1021/acs.jmedchem.0c01316. Epub 2020 Oct 2. J Med Chem. 2020. PMID: 32955874

2

Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.

Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou CP, Liepouri F, Mettou A, Katsoulis I, Maranti A, Tsiliouka K, Strongilos A, Chaitidou S, Douni E, Kontopidis G, Kollias G, Couladouros E, Eliopoulos E. Alexiou P, et al. Arch Pharm (Weinheim). 2014 Nov;347(11):798-805. doi: 10.1002/ardp.201400198. Epub 2014 Aug 27. Arch Pharm (Weinheim). 2014. PMID: 25160057

3

Aqueous Solubility Enhancement for Bioassays of Insoluble Inhibitors and QSPR Analysis: A TNF-α Study.

Mettou A, Papaneophytou C, Melagraki G, Maranti A, Liepouri F, Alexiou P, Papakyriakou A, Couladouros E, Eliopoulos E, Afantitis A, Kontopidis G. Mettou A, et al. Among authors: alexiou p. SLAS Discov. 2018 Jan;23(1):84-93. doi: 10.1177/2472555217712507. Epub 2017 Jun 6. SLAS Discov. 2018. PMID: 28586633 Free article.

4

A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.

Alexiou P, Demopoulos VJ. Alexiou P, et al. J Med Chem. 2010 Nov 11;53(21):7756-66. doi: 10.1021/jm101008m. J Med Chem. 2010. PMID: 20936791

5

Novel curcumin derivatives as P-glycoprotein inhibitors: Molecular modeling, synthesis and sensitization of multidrug resistant cells to doxorubicin.

Sagnou M, Novikov FN, Ivanova ES, Alexiou P, Stroylov VS, Titov IY, Tatarskiy VV, Vagida MS, Pelecanou M, Shtil AA, Chilov GG. Sagnou M, et al. Among authors: alexiou p. Eur J Med Chem. 2020 Jul 15;198:112331. doi: 10.1016/j.ejmech.2020.112331. Epub 2020 May 4. Eur J Med Chem. 2020. PMID: 32403017

6

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors.

Alexiou P, Nicolaou I, Stefek M, Kristl A, Demopoulos VJ. Alexiou P, et al. Bioorg Med Chem. 2008 Apr 1;16(7):3926-32. doi: 10.1016/j.bmc.2008.01.042. Epub 2008 Jan 30. Bioorg Med Chem. 2008. PMID: 18267362

7

RAGE: a multi-ligand receptor unveiling novel insights in health and disease.

Alexiou P, Chatzopoulou M, Pegklidou K, Demopoulos VJ. Alexiou P, et al. Curr Med Chem. 2010;17(21):2232-52. doi: 10.2174/092986710791331086. Curr Med Chem. 2010. PMID: 20459381 Review.

8

Aldose reductase enzyme and its implication to major health problems of the 21(st) century.

Alexiou P, Pegklidou K, Chatzopoulou M, Nicolaou I, Demopoulos VJ. Alexiou P, et al. Curr Med Chem. 2009;16(6):734-52. doi: 10.2174/092986709787458362. Curr Med Chem. 2009. PMID: 19199934 Review.

9

Novel aldose reductase inhibitors: a patent survey (2006--present).

Chatzopoulou M, Alexiou P, Kotsampasakou E, Demopoulos VJ. Chatzopoulou M, et al. Among authors: alexiou p. Expert Opin Ther Pat. 2012 Nov;22(11):1303-23. doi: 10.1517/13543776.2012.726615. Epub 2012 Sep 24. Expert Opin Ther Pat. 2012. PMID: 22998509 Review.

10

Curcumin derivatives as photosensitizers in photodynamic therapy: photophysical properties and in vitro studies with prostate cancer cells.

Kazantzis KT, Koutsonikoli K, Mavroidi B, Zachariadis M, Alexiou P, Pelecanou M, Politopoulos K, Alexandratou E, Sagnou M. Kazantzis KT, et al. Among authors: alexiou p. Photochem Photobiol Sci. 2020 Feb 19;19(2):193-206. doi: 10.1039/c9pp00375d. Photochem Photobiol Sci. 2020. PMID: 31956888

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