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Monotherapy efficacy of blood-brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma.
Merisaari J, Denisova OV, Doroszko M, Le Joncour V, Johansson P, Leenders WPJ, Kastrinsky DB, Zaware N, Narla G, Laakkonen P, Nelander S, Ohlmeyer M, Westermarck J. Merisaari J, et al. Among authors: laakkonen p. Brain Commun. 2020 Jan 11;2(1):fcaa002. doi: 10.1093/braincomms/fcaa002. eCollection 2020. Brain Commun. 2020. PMID: 32954276 Free PMC article.
PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells.
Kaur A, Denisova OV, Qiao X, Jumppanen M, Peuhu E, Ahmed SU, Raheem O, Haapasalo H, Eriksson J, Chalmers AJ, Laakkonen P, Westermarck J. Kaur A, et al. Among authors: laakkonen p. Cancer Res. 2016 Dec 1;76(23):7001-7011. doi: 10.1158/0008-5472.CAN-16-1134. Epub 2016 Sep 26. Cancer Res. 2016. PMID: 27671680
Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization.
Le Joncour V, Filppu P, Hyvönen M, Holopainen M, Turunen SP, Sihto H, Burghardt I, Joensuu H, Tynninen O, Jääskeläinen J, Weller M, Lehti K, Käkelä R, Laakkonen P. Le Joncour V, et al. Among authors: laakkonen p. EMBO Mol Med. 2019 Jun;11(6):e9034. doi: 10.15252/emmm.201809034. EMBO Mol Med. 2019. PMID: 31068339 Free PMC article.
Prostate-specific membrane antigen expression in the vasculature of primary lung carcinomas associates with faster metastatic dissemination to the brain.
Tanjore Ramanathan J, Lehtipuro S, Sihto H, Tóvári J, Reiniger L, Téglási V, Moldvay J, Nykter M, Haapasalo H, Le Joncour V, Laakkonen P. Tanjore Ramanathan J, et al. Among authors: laakkonen p. J Cell Mol Med. 2020 Jun;24(12):6916-6927. doi: 10.1111/jcmm.15350. Epub 2020 May 11. J Cell Mol Med. 2020. PMID: 32390293 Free PMC article.
89 results