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Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.
Welker A, Kersten C, Müller C, Madhugiri R, Zimmer C, Müller P, Zimmermann R, Hammerschmidt S, Maus H, Ziebuhr J, Sotriffer C, Schirmeister T. Welker A, et al. Among authors: sotriffer c. ChemMedChem. 2021 Jan 19;16(2):340-354. doi: 10.1002/cmdc.202000548. Epub 2020 Oct 16. ChemMedChem. 2021. PMID: 32930481 Free PMC article.
Glycolytic flux control by drugging phosphoglycolate phosphatase.
Jeanclos E, Schlötzer J, Hadamek K, Yuan-Chen N, Alwahsh M, Hollmann R, Fratz S, Yesilyurt-Gerhards D, Frankenbach T, Engelmann D, Keller A, Kaestner A, Schmitz W, Neuenschwander M, Hergenröder R, Sotriffer C, von Kries JP, Schindelin H, Gohla A. Jeanclos E, et al. Among authors: sotriffer c. Nat Commun. 2022 Nov 11;13(1):6845. doi: 10.1038/s41467-022-34228-2. Nat Commun. 2022. PMID: 36369173 Free PMC article.
Protocol for rational design of covalently interacting inhibitors.
Schmidt TC, Welker A, Rieger M, Sahu PK, Sotriffer CA, Schirmeister T, Engels B. Schmidt TC, et al. Among authors: sotriffer ca. Chemphyschem. 2014 Oct 20;15(15):3226-35. doi: 10.1002/cphc.201402542. Epub 2014 Sep 24. Chemphyschem. 2014. PMID: 25251382
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2 R Ligands To Combat Neurodegenerative Disorders.
Dolles D, Nimczick M, Scheiner M, Ramler J, Stadtmüller P, Sawatzky E, Drakopoulos A, Sotriffer C, Wittmann HJ, Strasser A, Decker M. Dolles D, et al. Among authors: sotriffer c. ChemMedChem. 2016 Jun 20;11(12):1270-83. doi: 10.1002/cmdc.201500418. Epub 2015 Nov 9. ChemMedChem. 2016. PMID: 26548365
Structure-Based Design and Synthesis of Covalent Inhibitors for Deubiquitinase and Acetyltransferase ChlaDUB1 of Chlamydia trachomatis.
Zimmermann T, Feng J, de Campos LJ, Knight LA, Schlötzer J, Ramirez YA, Schwickert K, Zehe M, Adler TB, Schirmeister T, Kisker C, Sotriffer C, Conda-Sheridan M, Decker M. Zimmermann T, et al. Among authors: sotriffer c. J Med Chem. 2024 Jul 11;67(13):10710-10742. doi: 10.1021/acs.jmedchem.4c00230. Epub 2024 Jun 19. J Med Chem. 2024. PMID: 38897928
112 results