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Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis.
Niyonzima N, Bakke SS, Gregersen I, Holm S, Sandanger Ø, Orrem HL, Sporsheim B, Ryan L, Kong XY, Dahl TB, Skjelland M, Sørensen KK, Rokstad AM, Yndestad A, Latz E, Gullestad L, Andersen GØ, Damås JK, Aukrust P, Mollnes TE, Halvorsen B, Espevik T. Niyonzima N, et al. Among authors: espevik t. EBioMedicine. 2020 Oct;60:102985. doi: 10.1016/j.ebiom.2020.102985. Epub 2020 Sep 11. EBioMedicine. 2020. PMID: 32927275 Free PMC article.
NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis.
Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A. Paramel Varghese G, et al. Among authors: espevik t. J Am Heart Assoc. 2016 May 20;5(5):e003031. doi: 10.1161/JAHA.115.003031. J Am Heart Assoc. 2016. PMID: 27207962 Free PMC article.
Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation.
Gregersen I, Sandanger Ø, Askevold ET, Sagen EL, Yang K, Holm S, Pedersen TM, Skjelland M, Krohg-Sørensen K, Hansen TV, Dahl TB, Otterdal K, Espevik T, Aukrust P, Yndestad A, Halvorsen B. Gregersen I, et al. Among authors: espevik t. PLoS One. 2017 Nov 27;12(11):e0188387. doi: 10.1371/journal.pone.0188387. eCollection 2017. PLoS One. 2017. PMID: 29176764 Free PMC article.
A vital role for complement in heart disease.
Lappegård KT, Garred P, Jonasson L, Espevik T, Aukrust P, Yndestad A, Mollnes TE, Hovland A. Lappegård KT, et al. Among authors: espevik t. Mol Immunol. 2014 Oct;61(2):126-34. doi: 10.1016/j.molimm.2014.06.036. Epub 2014 Jul 16. Mol Immunol. 2014. PMID: 25037633 Free article. Review.
301 results