Koštrun S - Search Results

1

Design, synthesis, antitrypanosomal activity, DNA/RNA binding and in vitro ADME profiling of novel imidazoline-substituted 2-arylbenzimidazoles.

Popov AB, Krstulović L, Koštrun S, Jelić D, Bokulić A, Stojković MR, Zonjić I, Taylor MC, Kelly JM, Bajić M, Raić-Malić S. Popov AB, et al. Among authors: kostrun s. Eur J Med Chem. 2020 Dec 1;207:112802. doi: 10.1016/j.ejmech.2020.112802. Epub 2020 Sep 6. Eur J Med Chem. 2020. PMID: 32927230

2

Synthesis, biological activity and molecular modeling studies of novel COX-1 inhibitors.

Martić M, Tatić I, Marković S, Kujundzić N, Kostrun S. Martić M, et al. Among authors: kostrun s. Eur J Med Chem. 2004 Feb;39(2):141-51. doi: 10.1016/j.ejmech.2003.11.011. Eur J Med Chem. 2004. PMID: 14987823

3

Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes.

Jelić D, Mildner B, Kostrun S, Nujić K, Verbanac D, Culić O, Antolović R, Brandt W. Jelić D, et al. Among authors: kostrun s. J Med Chem. 2007 Mar 22;50(6):1090-100. doi: 10.1021/jm0607202. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315853

4

Modeling cellular pharmacokinetics of 14- and 15-membered macrolides with physicochemical properties.

Stepanić V, Koštrun S, Malnar I, Hlevnjak M, Butković K, Ćaleta I, Dukši M, Kragol G, Makaruha-Stegić O, Mikac L, Ralić J, Tatić I, Tavčar B, Valko K, Zulfikari S, Munić V. Stepanić V, et al. Among authors: kostrun s. J Med Chem. 2011 Feb 10;54(3):719-33. doi: 10.1021/jm101317f. Epub 2011 Jan 5. J Med Chem. 2011. PMID: 21207938

5

Physicochemical profile of macrolides and their comparison with small molecules.

Stepanić V, Ziher D, Gabelica-Marković V, Jelić D, Nunhuck S, Valko K, Koštrun S. Stepanić V, et al. Among authors: kostrun s. Eur J Med Chem. 2012 Jan;47(1):462-72. doi: 10.1016/j.ejmech.2011.11.016. Epub 2011 Nov 17. Eur J Med Chem. 2012. PMID: 22152985

6

N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity.

Bosnar M, Kragol G, Koštrun S, Vujasinović I, Bošnjak B, Bencetić Mihaljević V, Marušić Ištuk Z, Kapić S, Hrvačić B, Brajša K, Tavčar B, Jelić D, Glojnarić I, Verbanac D, Culić O, Padovan J, Alihodžić S, Eraković Haber V, Spaventi R. Bosnar M, et al. Among authors: kostrun s. J Med Chem. 2012 Jul 12;55(13):6111-23. doi: 10.1021/jm300356u. Epub 2012 Jun 25. J Med Chem. 2012. PMID: 22697905

7

Antiproliferative activity of amino substituted benzo[b]thieno[2,3-b]pyrido[1,2-a]benzimidazoles explored by 2D and 3D cell culture system.

Perin N, Bobanović K, Zlatar I, Jelić D, Kelava V, Koštrun S, Marković VG, Brajša K, Hranjec M. Perin N, et al. Among authors: kostrun s. Eur J Med Chem. 2017 Jan 5;125:722-735. doi: 10.1016/j.ejmech.2016.09.084. Epub 2016 Sep 26. Eur J Med Chem. 2017. PMID: 27721156

8

Around the macrolide - Impact of 3D structure of macrocycles on lipophilicity and cellular accumulation.

Koštrun S, Munic Kos V, Matanović Škugor M, Palej Jakopović I, Malnar I, Dragojević S, Ralić J, Alihodžić S. Koštrun S, et al. Eur J Med Chem. 2017 Jun 16;133:351-364. doi: 10.1016/j.ejmech.2017.03.056. Epub 2017 Mar 27. Eur J Med Chem. 2017. PMID: 28410508

9

Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer.

Bistrović A, Krstulović L, Harej A, Grbčić P, Sedić M, Koštrun S, Pavelić SK, Bajić M, Raić-Malić S. Bistrović A, et al. Among authors: kostrun s. Eur J Med Chem. 2018 Jan 1;143:1616-1634. doi: 10.1016/j.ejmech.2017.10.061. Epub 2017 Nov 11. Eur J Med Chem. 2018. PMID: 29133046

10

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549.

Bistrović A, Grbčić P, Harej A, Sedić M, Kraljević-Pavelić S, Koštrun S, Plavec J, Makuc D, Raić-Malić S. Bistrović A, et al. Among authors: kostrun s. J Enzyme Inhib Med Chem. 2018 Dec;33(1):271-285. doi: 10.1080/14756366.2017.1414807. J Enzyme Inhib Med Chem. 2018. PMID: 29271659 Free PMC article.

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