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Page 1
Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer.
de Streel G, Bertrand C, Chalon N, Liénart S, Bricard O, Lecomte S, Devreux J, Gaignage M, De Boeck G, Mariën L, Van De Walle I, van der Woning B, Saunders M, de Haard H, Vermeersch E, Maes W, Deckmyn H, Coulie PG, van Baren N, Lucas S. de Streel G, et al. Among authors: bricard o. Nat Commun. 2020 Sep 11;11(1):4545. doi: 10.1038/s41467-020-17811-3. Nat Commun. 2020. PMID: 32917858 Free PMC article.
Facts and Hopes in Cancer Antigens Recognized by T Cells.
Brochier W, Bricard O, Coulie PG. Brochier W, et al. Among authors: bricard o. Clin Cancer Res. 2023 Jan 17;29(2):309-315. doi: 10.1158/1078-0432.CCR-21-3798. Clin Cancer Res. 2023. PMID: 36044396 Review.
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Whyte CE, Singh K, Burton OT, Aloulou M, Kouser L, Veiga RV, Dashwood A, Okkenhaug H, Benadda S, Moudra A, Bricard O, Lienart S, Bielefeld P, Roca CP, Naranjo-Galindo FJ, Lombard-Vadnais F, Junius S, Bending D, Ono MM, Hochepied T, Halim TYF, Schlenner S, Lesage S, Dooley J, Liston A. Whyte CE, et al. Among authors: bricard o. J Exp Med. 2022 Jul 4;219(7):e20212391. doi: 10.1084/jem.20212391. Epub 2022 Jun 14. J Exp Med. 2022. PMID: 35699942 Free PMC article.
Correction: Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits.
Whyte CE, Singh K, Burton OT, Aloulou M, Kouser L, Veiga RV, Dashwood A, Okkenhaug H, Benadda S, Moudra A, Bricard O, Lienart S, Bielefeld P, Roca CP, Naranjo-Galindo FJ, Lombard-Vadnais F, Junius S, Bending D, Ono M, Hochepied T, Halim TYF, Schlenner S, Lesage S, Dooley J, Liston A. Whyte CE, et al. Among authors: bricard o. J Exp Med. 2022 Aug 1;219(8):jem.2021149805312022c. doi: 10.1084/jem.2021239107142022c. Epub 2022 Jul 25. J Exp Med. 2022. PMID: 35878878 Free PMC article. No abstract available.
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program.
Burton OT, Bricard O, Tareen S, Gergelits V, Andrews S, Biggins L, Roca CP, Whyte C, Junius S, Brajic A, Pasciuto E, Ali M, Lemaitre P, Schlenner SM, Ishigame H, Brown BD, Dooley J, Liston A. Burton OT, et al. Among authors: bricard o. Immunity. 2024 Jul 9;57(7):1586-1602.e10. doi: 10.1016/j.immuni.2024.05.023. Epub 2024 Jun 18. Immunity. 2024. PMID: 38897202 Free article.
CD4+ T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy.
Franken A, Bila M, Mechels A, Kint S, Van Dessel J, Pomella V, Vanuytven S, Philips G, Bricard O, Xiong J, Boeckx B, Hatse S, Van Brussel T, Schepers R, Van Aerde C, Geurs S, Vandecaveye V, Hauben E, Vander Poorten V, Verbandt S, Vandereyken K, Qian J, Tejpar S, Voet T, Clement PM, Lambrechts D. Franken A, et al. Among authors: bricard o. Immunity. 2024 Mar 12;57(3):541-558.e7. doi: 10.1016/j.immuni.2024.02.007. Epub 2024 Mar 4. Immunity. 2024. PMID: 38442708
PD-1- CD45RA+ effector-memory CD8 T cells and CXCL10+ macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma.
Cappuyns S, Philips G, Vandecaveye V, Boeckx B, Schepers R, Van Brussel T, Arijs I, Mechels A, Bassez A, Lodi F, Jaekers J, Topal H, Topal B, Bricard O, Qian J, Van Cutsem E, Verslype C, Lambrechts D, Dekervel J. Cappuyns S, et al. Among authors: bricard o. Nat Commun. 2023 Nov 29;14(1):7825. doi: 10.1038/s41467-023-43381-1. Nat Commun. 2023. PMID: 38030622 Free PMC article.