Yang H - Search Results

1

Development of a Tau-Targeted Drug Delivery System Using a Multifunctional Nanoscale Metal-Organic Framework for Alzheimer's Disease Therapy.

Zhao J, Yin F, Ji L, Wang C, Shi C, Liu X, Yang H, Wang X, Kong L. Zhao J, et al. Among authors: yang h. ACS Appl Mater Interfaces. 2020 Oct 7;12(40):44447-44458. doi: 10.1021/acsami.0c11064. Epub 2020 Sep 16. ACS Appl Mater Interfaces. 2020. PMID: 32897042

2

Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-β aggregation for the treatment of Alzheimer's disease.

Yang HL, Cai P, Liu QH, Yang XL, Li F, Wang J, Wu JJ, Wang XB, Kong LY. Yang HL, et al. Eur J Med Chem. 2017 Sep 29;138:715-728. doi: 10.1016/j.ejmech.2017.07.008. Epub 2017 Jul 8. Eur J Med Chem. 2017. PMID: 28728104

3

Design, synthesis, and evaluation of salicyladimine derivatives as multitarget-directed ligands against Alzheimer's disease.

Yang HL, Cai P, Liu QH, Yang XL, Fang SQ, Tang YW, Wang C, Wang XB, Kong LY. Yang HL, et al. Bioorg Med Chem. 2017 Nov 1;25(21):5917-5928. doi: 10.1016/j.bmc.2017.08.048. Epub 2017 Sep 27. Bioorg Med Chem. 2017. PMID: 28988627

4

Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.

Cai P, Fang SQ, Yang HL, Yang XL, Liu QH, Kong LY, Wang XB. Cai P, et al. Eur J Med Chem. 2018 Sep 5;157:161-176. doi: 10.1016/j.ejmech.2018.08.005. Epub 2018 Aug 4. Eur J Med Chem. 2018. PMID: 30096650

5

Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease.

Tang YW, Shi CJ, Yang HL, Cai P, Liu QH, Yang XL, Kong LY, Wang XB. Tang YW, et al. Eur J Med Chem. 2019 Feb 1;163:307-319. doi: 10.1016/j.ejmech.2018.11.040. Epub 2018 Nov 26. Eur J Med Chem. 2019. PMID: 30529634

6

Palladium-Catalyzed meta-C-H Olefination of Arene-Tethered Diols Directed by Well-Designed Pyrimidine-Based Group.

Fang S, Wang X, Yin F, Cai P, Yang H, Kong L. Fang S, et al. Among authors: yang h. Org Lett. 2019 Mar 15;21(6):1841-1844. doi: 10.1021/acs.orglett.9b00433. Epub 2019 Mar 6. Org Lett. 2019. PMID: 30840472

7

A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease.

Yang HL, Fang SQ, Tang YW, Wang C, Luo H, Qu LL, Zhao JH, Shi CJ, Yin FC, Wang XB, Kong LY. Yang HL, et al. Eur J Med Chem. 2019 Oct 1;179:736-743. doi: 10.1016/j.ejmech.2019.07.005. Epub 2019 Jul 2. Eur J Med Chem. 2019. PMID: 31284083

8

Usnic acid derivatives as tau-aggregation and neuroinflammation inhibitors.

Shi CJ, Peng W, Zhao JH, Yang HL, Qu LL, Wang C, Kong LY, Wang XB. Shi CJ, et al. Eur J Med Chem. 2020 Feb 1;187:111961. doi: 10.1016/j.ejmech.2019.111961. Epub 2019 Dec 12. Eur J Med Chem. 2020. PMID: 31865017

9

Design and SAR of Withangulatin A Analogues that Act as Covalent TrxR Inhibitors through the Michael Addition Reaction Showing Potential in Cancer Treatment.

Wang C, Li S, Zhao J, Yang H, Yin F, Ding M, Luo J, Wang X, Kong L. Wang C, et al. Among authors: yang h. J Med Chem. 2020 Oct 8;63(19):11195-11214. doi: 10.1021/acs.jmedchem.0c01128. Epub 2020 Sep 17. J Med Chem. 2020. PMID: 32886510

10

Identification and optimization of piperlongumine analogues as potential antioxidant and anti-inflammatory agents via activation of Nrf2.

Ji L, Qu L, Wang C, Peng W, Li S, Yang H, Luo H, Yin F, Lu D, Liu X, Kong L, Wang X. Ji L, et al. Among authors: yang h. Eur J Med Chem. 2021 Jan 15;210:112965. doi: 10.1016/j.ejmech.2020.112965. Epub 2020 Oct 27. Eur J Med Chem. 2021. PMID: 33148493

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