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Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Austin M, Burschowsky D, Chan DTY, Jenkinson L, Haynes S, Diamandakis A, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Hadjinicolaou AV, Gileadi U, Gowans E, Shibata Y, Barnard M, Kaserer T, Sharma P, Luheshi NM, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Austin M, et al. Among authors: ryman s. MAbs. 2020 Jan-Dec;12(1):1801230. doi: 10.1080/19420862.2020.1801230. MAbs. 2020. PMID: 32880207 Free PMC article.
Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Chan DTY, Jenkinson L, Haynes SW, Austin M, Diamandakis A, Burschowsky D, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Gowans E, Shibata Y, Barnard M, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Chan DTY, et al. Among authors: ryman s. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16949-16960. doi: 10.1073/pnas.1919565117. Epub 2020 Jul 2. Proc Natl Acad Sci U S A. 2020. PMID: 32616569 Free PMC article.
Diffusion magnetic resonance spectroscopy captures microglial reactivity related to gut-derived systemic lipopolysaccharide: A preliminary study.
Birg A, van der Horn HJ, Ryman SG, Branzoli F, Deelchand DK, Quinn DK, Mayer AR, Lin HC, Erhardt EB, Caprihan A, Zotev V, Parada AN, Wick TV, Matos YL, Barnhart KA, Nitschke SR, Shaff NA, Julio KR, Prather HE, Vakhtin AA. Birg A, et al. Among authors: ryman sg. Brain Behav Immun. 2024 Nov;122:345-352. doi: 10.1016/j.bbi.2024.08.034. Epub 2024 Aug 18. Brain Behav Immun. 2024. PMID: 39163909 Free article.
Alterations of cerebrovascular reactivity following pediatric mild traumatic brain injury are independent of neurodevelopmental changes.
van der Horn HJ, Dodd AB, Wick TV, Robertson-Benta C, McQuaid JR, Erhardt EB, Miller SD, Sasi Kumar D, Nathaniel U, Ling JM, Ryman SG, Vakhtin AA, Sapien RE, Phillips JP, Campbell RA, Mayer AR. van der Horn HJ, et al. Among authors: ryman sg. J Cereb Blood Flow Metab. 2024 Aug 7:271678X241270531. doi: 10.1177/0271678X241270531. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39113416 Free PMC article.
Parkinson's disease cerebrovascular reactivity pattern: A feasibility study.
van der Horn HJ, Vakhtin AA, Julio K, Nitschke S, Shaff N, Dodd AB, Erhardt E, Phillips JP, Pirio Richardson S, Deligtisch A, Stewart M, Suarez Cedeno G, Meles SK, Mayer AR, Ryman SG. van der Horn HJ, et al. Among authors: ryman sg. J Cereb Blood Flow Metab. 2024 Oct;44(10):1774-1786. doi: 10.1177/0271678X241241895. Epub 2024 Apr 5. J Cereb Blood Flow Metab. 2024. PMID: 38578669
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease.
Rutledge J, Lehallier B, Zarifkar P, Losada PM, Shahid-Besanti M, Western D, Gorijala P, Ryman S, Yutsis M, Deutsch GK, Mormino E, Trelle A, Wagner AD, Kerchner GA, Tian L, Cruchaga C, Henderson VW, Montine TJ, Borghammer P, Wyss-Coray T, Poston KL. Rutledge J, et al. Among authors: ryman s. Acta Neuropathol. 2024 Mar 11;147(1):52. doi: 10.1007/s00401-024-02706-0. Acta Neuropathol. 2024. PMID: 38467937 Free PMC article.
52 results