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153 results

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Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Austin M, Burschowsky D, Chan DTY, Jenkinson L, Haynes S, Diamandakis A, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Hadjinicolaou AV, Gileadi U, Gowans E, Shibata Y, Barnard M, Kaserer T, Sharma P, Luheshi NM, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Austin M, et al. Among authors: gowans e. MAbs. 2020 Jan-Dec;12(1):1801230. doi: 10.1080/19420862.2020.1801230. MAbs. 2020. PMID: 32880207 Free PMC article.
Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Chan DTY, Jenkinson L, Haynes SW, Austin M, Diamandakis A, Burschowsky D, Seewooruthun C, Addyman A, Fiedler S, Ryman S, Whitehouse J, Slater LH, Gowans E, Shibata Y, Barnard M, Wilkinson RW, Vaughan TJ, Holt SV, Cerundolo V, Carr MD, Groves MAT. Chan DTY, et al. Among authors: gowans e. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):16949-16960. doi: 10.1073/pnas.1919565117. Epub 2020 Jul 2. Proc Natl Acad Sci U S A. 2020. PMID: 32616569 Free PMC article.
SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents.
Garcia-Valtanen P, Hope CM, Masavuli MG, Yeow AEL, Balachandran H, Mekonnen ZA, Al-Delfi Z, Abayasingam A, Agapiou D, Stella AO, Aggarwal A, Bouras G, Gummow J, Ferguson C, O'Connor S, McCartney EM, Lynn DJ, Maddern G, Gowans EJ, Reddi BAJ, Shaw D, Kok-Lim C, Beard MR, Weiskopf D, Sette A, Turville SG, Bull RA, Barry SC, Grubor-Bauk B. Garcia-Valtanen P, et al. Among authors: gowans ej. Cell Rep Med. 2022 Jun 21;3(6):100651. doi: 10.1016/j.xcrm.2022.100651. Epub 2022 May 17. Cell Rep Med. 2022. PMID: 35654046 Free PMC article.
Achieving safe surgery after COVID-19 vaccination.
Kovoor JG, Jacobsen JHW, Duncan J, Addo AA, Tivey DR, Babidge WJ, Penn D, Churchill J, Collinson TG, Kok J, Kelly S, Lu VH, Beavis VS, MacCormick AD, Kearney BJ, Gowans EJ, Hewett PJ, Hugh TJ, Woo HH, Padbury RT, Scott DA, Frydenberg M, Maddern GJ. Kovoor JG, et al. Among authors: gowans ej. ANZ J Surg. 2022 May;92(5):946-949. doi: 10.1111/ans.17654. ANZ J Surg. 2022. PMID: 35535005 Free PMC article. No abstract available.
Safety Profile of a Multi-Antigenic DNA Vaccine Against Hepatitis C Virus.
Gummow J, Masavuli MG, Mekonnen ZA, Li Y, Wijesundara DK, Shrestha AC, Voskoboinik I, Gowans EJ, Grubor-Bauk B. Gummow J, et al. Among authors: gowans ej. Vaccines (Basel). 2020 Jan 29;8(1):53. doi: 10.3390/vaccines8010053. Vaccines (Basel). 2020. PMID: 32013228 Free PMC article.
NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice.
Grubor-Bauk B, Wijesundara DK, Masavuli M, Abbink P, Peterson RL, Prow NA, Larocca RA, Mekonnen ZA, Shrestha A, Eyre NS, Beard MR, Gummow J, Carr J, Robertson SA, Hayball JD, Barouch DH, Gowans EJ. Grubor-Bauk B, et al. Among authors: gowans ej. Sci Adv. 2019 Dec 11;5(12):eaax2388. doi: 10.1126/sciadv.aax2388. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31844662 Free PMC article.
Single-Dose Vaccination with a Hepatotropic Adeno-associated Virus Efficiently Localizes T Cell Immunity in the Liver with the Potential To Confer Rapid Protection against Hepatitis C Virus.
Mekonnen ZA, Grubor-Bauk B, English K, Leung P, Masavuli MG, Shrestha AC, Bertolino P, Bowen DG, Lloyd AR, Gowans EJ, Wijesundara DK. Mekonnen ZA, et al. Among authors: gowans ej. J Virol. 2019 Sep 12;93(19):e00202-19. doi: 10.1128/JVI.00202-19. Print 2019 Oct 1. J Virol. 2019. PMID: 31292249 Free PMC article.
153 results