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A comparative analysis of SARS-CoV-2 antivirals in human airway models characterizes 3CLpro inhibitor PF-00835231 as a potential new treatment for COVID-19.
de Vries M, Mohamed AS, Prescott RA, Valero-Jimenez AM, Desvignes L, O'Connor R, Steppan C, Devlin JC, Ivanova E, Herrera A, Schinlever A, Loose P, Ruggles K, Koralov SB, Anderson AS, Binder J, Dittmann M. de Vries M, et al. Among authors: koralov sb. bioRxiv [Preprint]. 2021 Feb 19:2020.08.28.272880. doi: 10.1101/2020.08.28.272880. bioRxiv. 2021. Update in: J Virol. 2021 Feb 23;95(7):JVI.01819-20. doi: 10.1128/JVI.01819-20 PMID: 32869028 Free PMC article. Updated. Preprint.
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection.
Ivanova EN, Shwetar J, Devlin JC, Buus TB, Gray-Gaillard S, Koide A, Cornelius A, Samanovic MI, Herrera A, Mimitou EP, Zhang C, Karmacharya T, Desvignes L, Ødum N, Smibert P, Ulrich RJ, Mulligan MJ, Koide S, Ruggles KV, Herati RS, Koralov SB. Ivanova EN, et al. Among authors: koralov sb. iScience. 2023 Nov 24;26(12):108572. doi: 10.1016/j.isci.2023.108572. eCollection 2023 Dec 15. iScience. 2023. PMID: 38213787 Free PMC article.
Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.
Sulaiman I, Chung M, Angel L, Koralov S, Wu B, Yeung S, Krolikowski K, Li Y, Duerr R, Schluger R, Thannickal S, Koide A, Rafeq S, Barnett C, Postelnicu R, Wang C, Banakis S, Perez-Perez L, Jour G, Shen G, Meyn P, Carpenito J, Liu X, Ji K, Collazo D, Labarbiera A, Amoroso N, Brosnahan S, Mukherjee V, Kaufman D, Bakker J, Lubinsky A, Pradhan D, Sterman D, Heguy A, Uyeki T, Clemente J, de Wit E, Schmidt AM, Shopsin B, Desvignes L, Wang C, Li H, Zhang B, Forst C, Koide S, Stapleford K, Khanna K, Ghedin E, Weiden M, Segal L. Sulaiman I, et al. Res Sq [Preprint]. 2021 Mar 29:rs.3.rs-266050. doi: 10.21203/rs.3.rs-266050/v1. Res Sq. 2021. Update in: Nat Microbiol. 2021 Oct;6(10):1245-1258. doi: 10.1038/s41564-021-00961-5 PMID: 33791687 Free PMC article. Updated. Preprint.
Skin immune-mesenchymal interplay within tertiarylymphoid structures promotes autoimmunepathogenesis in hidradenitis suppurativa.
Yu WW, Barrett JNP, Tong J, Lin MJ, Marohn M, Devlin JC, Herrera A, Remark J, Levine J, Liu PK, Fang V, Zellmer AM, Oldridge DA, Wherry EJ, Lin JR, Chen JY, Sorger P, Santagata S, Krueger JG, Ruggles KV, Wang F, Su C, Koralov SB, Wang J, Chiu ES, Lu CP. Yu WW, et al. Among authors: koralov sb. Immunity. 2024 Dec 10;57(12):2827-2842.e5. doi: 10.1016/j.immuni.2024.11.010. Immunity. 2024. PMID: 39662091
A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia.
Chakraborty S, Morganti C, Pena BR, Zhang H, Verma D, Zaldana K, Gitego N, Ma F, Aluri S, Pradhan K, Gordon S, Mantzaris I, Goldfinger M, Feldman E, Gritsman K, Shi Y, Hubner S, Qiu YH, Brown BD, Skwarska A, Verma A, Konopleva M, Tabe Y, Gavathiotis E, Colla S, Gollob J, Dey J, Kornblau SM, Koralov SB, Ito K, Shastri A. Chakraborty S, et al. Among authors: koralov sb. bioRxiv [Preprint]. 2024 Aug 7:2024.08.05.599788. doi: 10.1101/2024.08.05.599788. bioRxiv. 2024. PMID: 39211137 Free PMC article. Preprint.
Preexisting Skin-Resident CD8 and γδ T-cell Circuits Mediate Immune Response in Merkel Cell Carcinoma and Predict Immunotherapy Efficacy.
Reinstein ZZ, Zhang Y, Ospina OE, Nichols MD, Chu VA, Pulido AM, Prieto K, Nguyen JV, Yin R, Moran Segura C, Usman A, Sell B, Ng S, de la Iglesia JV, Chandra S, Sosman JA, Cho RJ, Cheng JB, Ivanova E, Koralov SB, Slebos RJC, Chung CH, Khushalani NI, Messina JL, Sarnaik AA, Zager JS, Sondak VK, Vaske C, Kim S, Brohl AS, Mi X, Pierce BG, Wang X, Fridley BL, Tsai KY, Choi J. Reinstein ZZ, et al. Among authors: koralov sb. Cancer Discov. 2024 Sep 4;14(9):1631-1652. doi: 10.1158/2159-8290.CD-23-0798. Cancer Discov. 2024. PMID: 39058036
SARS-CoV-2 inflammation durably imprints memory CD4 T cells.
Gray-Gaillard SL, Solis SM, Chen HM, Monteiro C, Ciabattoni G, Samanovic MI, Cornelius AR, Williams T, Geesey E, Rodriguez M, Ortigoza MB, Ivanova EN, Koralov SB, Mulligan MJ, Herati RS. Gray-Gaillard SL, et al. Among authors: koralov sb. Sci Immunol. 2024 Jun 21;9(96):eadj8526. doi: 10.1126/sciimmunol.adj8526. Epub 2024 Jun 21. Sci Immunol. 2024. PMID: 38905326
Genetic and environmental interactions contribute to immune variation in rewilded mice.
Oyesola O, Downie AE, Howard N, Barre RS, Kiwanuka K, Zaldana K, Chen YH, Menezes A, Lee SC, Devlin J, Mondragón-Palomino O, Souza COS, Herrmann C, Koralov SB, Cadwell K, Graham AL, Loke P. Oyesola O, et al. Among authors: koralov sb. Nat Immunol. 2024 Jul;25(7):1270-1282. doi: 10.1038/s41590-024-01862-5. Epub 2024 Jun 14. Nat Immunol. 2024. PMID: 38877178 Free PMC article.
Keratinocytes Present Staphylococcus aureus Enterotoxins and Promote Malignant and Nonmalignant T Cell Proliferation in Cutaneous T-Cell Lymphoma.
Zeng Z, Vadivel CK, Gluud M, Namini MRJ, Yan L, Ahmad S, Hansen MB, Coquet J, Mustelin T, Koralov SB, Bonefeld CM, Woetmann A, Geisler C, Guenova E, Kamstrup MR, Litman T, Gjerdrum LR, Buus TB, Ødum N. Zeng Z, et al. Among authors: koralov sb. J Invest Dermatol. 2024 Dec;144(12):2789-2804.e10. doi: 10.1016/j.jid.2024.04.018. Epub 2024 May 16. J Invest Dermatol. 2024. PMID: 38762064 Free article.
106 results