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Covalent inhibition of NSD1 histone methyltransferase.
Huang H, Howard CA, Zari S, Cho HJ, Shukla S, Li H, Ndoj J, González-Alonso P, Nikolaidis C, Abbott J, Rogawski DS, Potopnyk MA, Kempinska K, Miao H, Purohit T, Henderson A, Mapp A, Sulis ML, Ferrando A, Grembecka J, Cierpicki T. Huang H, et al. Nat Chem Biol. 2020 Dec;16(12):1403-1410. doi: 10.1038/s41589-020-0626-6. Epub 2020 Aug 31. Nat Chem Biol. 2020. PMID: 32868895 Free PMC article.
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia.
Klossowski S, Miao H, Kempinska K, Wu T, Purohit T, Kim E, Linhares BM, Chen D, Jih G, Perkey E, Huang H, He M, Wen B, Wang Y, Yu K, Lee SC, Danet-Desnoyers G, Trotman W, Kandarpa M, Cotton A, Abdel-Wahab O, Lei H, Dou Y, Guzman M, Peterson L, Gruber T, Choi S, Sun D, Ren P, Li LS, Liu Y, Burrows F, Maillard I, Cierpicki T, Grembecka J. Klossowski S, et al. Among authors: huang h. J Clin Invest. 2020 Feb 3;130(2):981-997. doi: 10.1172/JCI129126. J Clin Invest. 2020. PMID: 31855575 Free PMC article.
Cancer-targeted pro-theranostic bi-metallic organo-coordination nanoparticles.
Huang H, Fang L, Wansapura J, Prior JL, Manion B, Xu B, Hongsermeier C, Gamadia N, Blasi N, Tang R, Egbulefu C, Shokeen M, Quirk JD, Achilefu S. Huang H, et al. Theranostics. 2025 Jan 1;15(4):1205-1220. doi: 10.7150/thno.99863. eCollection 2025. Theranostics. 2025. PMID: 39816680 Free PMC article.
An implantable system for opioid safety.
Huang HW, Chai PR, Lee S, Kerssemakers T, Imani A, Chen J, Heim M, Bo JY, Wentworth A, Sanoudos-Dramaliotis FT, Ballinger I, Maji S, Murphy M, Alexiev A, Kang GH, Fabian N, Jenkins J, Pettinari A, Ishida K, Li J, You SS, Hayward AM, Chandrakasan A, Traverso G. Huang HW, et al. Device. 2024 Oct 18;2(10):100517. doi: 10.1016/j.device.2024.100517. Epub 2024 Aug 14. Device. 2024. PMID: 39816527 Free PMC article.
41,893 results
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