Chen Y - Search Results

1

Chemical modification of ovatodiolide revealed a promising amino-prodrug with improved pharmacokinetic profile.

Xiang J , Zhang X , Wang D , Li J , Li Q , Wang Q , Ding Y , Chen T , Sun Y , Bao S , Chen J , Li D , Wang L , Chen Y . Xiang J , et al. Among authors: chen j, chen t, chen y. Chem Commun (Camb). 2020 Sep 25;56(75):11018-11021. doi: 10.1039/c9cc07573a. Epub 2020 Aug 28. Chem Commun (Camb). 2020. PMID: 32856652

2

Syntheses and Biological Evaluation of Costunolide, Parthenolide, and Their Fluorinated Analogues.

Yang ZJ, Ge WZ, Li QY, Lu Y, Gong JM, Kuang BJ, Xi X, Wu H, Zhang Q, Chen Y. Yang ZJ, et al. Among authors: chen y. J Med Chem. 2015 Sep 10;58(17):7007-20. doi: 10.1021/acs.jmedchem.5b00915. Epub 2015 Aug 20. J Med Chem. 2015. PMID: 26226279

3

Structure-Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4-Methylester-Rakicidin A.

Sang F, Ding Y, Wang J, Sun B, Sun J, Geng Y, Zhang Z, Ding K, Wu LL, Liu JW, Bai C, Yang G, Zhang Q, Li LY, Chen Y. Sang F, et al. Among authors: chen y. J Med Chem. 2016 Feb 11;59(3):1184-96. doi: 10.1021/acs.jmedchem.5b01841. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26814890

4

Dispirocyclopropyldehydrocostus lactone selectively inhibits acute myelogenous leukemia cells.

Ding YH, Gao X, Long J, Kuang BJ, Chen Y, Zhang Q. Ding YH, et al. Among authors: chen y. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1165-8. doi: 10.1016/j.bmcl.2016.01.046. Epub 2016 Jan 18. Bioorg Med Chem Lett. 2016. PMID: 26832219

5

Syntheses and biological evaluation of 1,2,3-triazole and 1,3,4-oxadiazole derivatives of imatinib.

Li YT, Wang JH, Pan CW, Meng FF, Chu XQ, Ding YH, Qu WZ, Li HY, Yang C, Zhang Q, Bai CG, Chen Y. Li YT, et al. Among authors: chen y. Bioorg Med Chem Lett. 2016 Mar 1;26(5):1419-27. doi: 10.1016/j.bmcl.2016.01.068. Epub 2016 Jan 23. Bioorg Med Chem Lett. 2016. PMID: 26850004

6

Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells.

Ding Y, Gao H, Zhang Y, Li Y, Vasdev N, Gao Y, Chen Y, Zhang Q. Ding Y, et al. Among authors: chen y. J Hematol Oncol. 2016 Sep 22;9(1):93. doi: 10.1186/s13045-016-0327-5. J Hematol Oncol. 2016. PMID: 27658462 Free PMC article.

7

Synthesis and anti-acute myeloid leukemia activity of C-14 modified parthenolide derivatives.

Yang Z, Kuang B, Kang N, Ding Y, Ge W, Lian L, Gao Y, Wei Y, Chen Y, Zhang Q. Yang Z, et al. Among authors: chen y. Eur J Med Chem. 2017 Feb 15;127:296-304. doi: 10.1016/j.ejmech.2016.12.044. Epub 2016 Dec 23. Eur J Med Chem. 2017. PMID: 28068601

8

Total Syntheses and Biological Activities of Vinylamycin Analogues.

Wang J, Kuang B, Guo X, Liu J, Ding Y, Li J, Jiang S, Liu Y, Bai F, Li L, Zhang Q, Zhu XY, Xia B, Li CQ, Wang L, Yang G, Chen Y. Wang J, et al. Among authors: chen y. J Med Chem. 2017 Feb 9;60(3):1189-1209. doi: 10.1021/acs.jmedchem.6b01745. Epub 2017 Jan 20. J Med Chem. 2017. PMID: 28075592

9

Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia.

Gao HE, Sun Y, Ding YH, Long J, Liu XL, Yang M, Ji Q, Li YH, Chen Y, Zhang Q, Gao YD. Gao HE, et al. Among authors: chen y. Oncotarget. 2017 Jun 13;8(24):38990-39000. doi: 10.18632/oncotarget.17166. Oncotarget. 2017. PMID: 28473664 Free PMC article.

10

Cyclic Depsipeptide BE-43547A₂ : Synthesis and Activity against Pancreatic Cancer Stem Cells.

Sun Y, Ding Y, Li D, Zhou R, Su X, Yang J, Guo X, Chong C, Wang J, Zhang W, Bai C, Wang L, Chen Y. Sun Y, et al. Among authors: chen y. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14627-14631. doi: 10.1002/anie.201709744. Epub 2017 Oct 24. Angew Chem Int Ed Engl. 2017. PMID: 28984401

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