Brough D - Search Results

1

Anakinra in COVID-19: important considerations for clinical trials.

King A, Vail A, O'Leary C, Hannan C, Brough D, Patel H, Galea J, Ogungbenro K, Wright M, Pathmanaban O, Hulme S, Allan S. King A, et al. Among authors: brough d. Lancet Rheumatol. 2020 Jul;2(7):e379-e381. doi: 10.1016/S2665-9913(20)30160-0. Epub 2020 May 21. Lancet Rheumatol. 2020. PMID: 32835233 Free PMC article. No abstract available.

2

Regulation of interleukin-1 in acute brain injury.

Brough D, Tyrrell PJ, Allan SM. Brough D, et al. Trends Pharmacol Sci. 2011 Oct;32(10):617-22. doi: 10.1016/j.tips.2011.06.002. Epub 2011 Jul 23. Trends Pharmacol Sci. 2011. PMID: 21788085 Review.

3

Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology.

Greenhalgh AD, Brough D, Robinson EM, Girard S, Rothwell NJ, Allan SM. Greenhalgh AD, et al. Among authors: brough d. Dis Model Mech. 2012 Nov;5(6):823-33. doi: 10.1242/dmm.008557. Epub 2012 May 31. Dis Model Mech. 2012. PMID: 22679224 Free PMC article.

4

Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen-glucose deprivation in organotypic brain slices.

Girard S, Brough D, Lopez-Castejon G, Giles J, Rothwell NJ, Allan SM. Girard S, et al. Among authors: brough d. Glia. 2013 May;61(5):813-24. doi: 10.1002/glia.22478. Epub 2013 Feb 13. Glia. 2013. PMID: 23404620 Free PMC article.

5

Acidosis drives damage-associated molecular pattern (DAMP)-induced interleukin-1 secretion via a caspase-1-independent pathway.

Edye ME, Lopez-Castejon G, Allan SM, Brough D. Edye ME, et al. Among authors: brough d. J Biol Chem. 2013 Oct 18;288(42):30485-30494. doi: 10.1074/jbc.M113.478941. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022484 Free PMC article.

6

The role of inflammation and interleukin-1 in acute cerebrovascular disease.

Galea J, Brough D. Galea J, et al. Among authors: brough d. J Inflamm Res. 2013 Aug 20;6:121-8. doi: 10.2147/JIR.S35629. J Inflamm Res. 2013. PMID: 24062616 Free PMC article. Review.

7

Interleukin-1 as a pharmacological target in acute brain injury.

Brough D, Rothwell NJ, Allan SM. Brough D, et al. Exp Physiol. 2015 Dec;100(12):1488-94. doi: 10.1113/EP085135. Epub 2015 Jul 14. Exp Physiol. 2015. PMID: 26096539 Free article. Review.

8

Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage.

Edye ME, Brough D, Allan SM. Edye ME, et al. Among authors: brough d. J Biol Chem. 2015 Oct 16;290(42):25374-81. doi: 10.1074/jbc.M115.667162. Epub 2015 Aug 31. J Biol Chem. 2015. PMID: 26324708 Free PMC article.

9

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.

Daniels MJ, Rivers-Auty J, Schilling T, Spencer NG, Watremez W, Fasolino V, Booth SJ, White CS, Baldwin AG, Freeman S, Wong R, Latta C, Yu S, Jackson J, Fischer N, Koziel V, Pillot T, Bagnall J, Allan SM, Paszek P, Galea J, Harte MK, Eder C, Lawrence CB, Brough D. Daniels MJ, et al. Among authors: brough d. Nat Commun. 2016 Aug 11;7:12504. doi: 10.1038/ncomms12504. Nat Commun. 2016. PMID: 27509875 Free PMC article.

10

Assessing Inflammation in Acute Intracerebral Hemorrhage with PK11195 PET and Dynamic Contrast-Enhanced MRI.

Abid KA, Sobowale OA, Parkes LM, Naish J, Parker GJM, du Plessis D, Brough D, Barrington J, Allan SM, Hinz R, Parry-Jones AR. Abid KA, et al. Among authors: brough d. J Neuroimaging. 2018 Mar;28(2):158-161. doi: 10.1111/jon.12477. Epub 2017 Oct 24. J Neuroimaging. 2018. PMID: 29064155

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