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Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice.
Motegi M, Himeno T, Nakai-Shimoda H, Inoue R, Ozeki N, Hayashi Y, Sasajima S, Mohiuddin MS, Asano-Hayami E, Kato M, Asano S, Miura-Yura E, Morishita Y, Kondo M, Tsunekawa S, Kato Y, Kato K, Naruse K, Seino Y, Hayashi Y, Nakamura J, Kamiya H. Motegi M, et al. Among authors: hayashi y. Biochem Biophys Res Commun. 2020 Oct 29;532(1):47-53. doi: 10.1016/j.bbrc.2020.08.007. Epub 2020 Aug 19. Biochem Biophys Res Commun. 2020. PMID: 32826056 Free article.
Ectopic expression of GIP in pancreatic β-cells maintains enhanced insulin secretion in mice with complete absence of proglucagon-derived peptides.
Fukami A, Seino Y, Ozaki N, Yamamoto M, Sugiyama C, Sakamoto-Miura E, Himeno T, Takagishi Y, Tsunekawa S, Ali S, Drucker DJ, Murata Y, Seino Y, Oiso Y, Hayashi Y. Fukami A, et al. Among authors: hayashi y. Diabetes. 2013 Feb;62(2):510-8. doi: 10.2337/db12-0294. Epub 2012 Oct 25. Diabetes. 2013. PMID: 23099862 Free PMC article.
KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state.
Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. Ogata H, et al. Among authors: hayashi y. J Endocrinol. 2014 Aug;222(2):191-200. doi: 10.1530/JOE-14-0161. Epub 2014 Jun 2. J Endocrinol. 2014. PMID: 24891433
Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin.
Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y. Iida A, et al. Among authors: hayashi y. Diabetologia. 2016 Jul;59(7):1533-1541. doi: 10.1007/s00125-016-3935-2. Epub 2016 Apr 6. Diabetologia. 2016. PMID: 27053237 Free PMC article.
8,274 results