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Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid.
Tsiailanis AD, Renziehausen A, Kiriakidi S, Vrettos EI, Markopoulos GS, Sayyad N, Hirmiz B, Aguilar MI, Del Borgo MP, Kolettas E, Widdop RE, Mavromoustakos T, Crook T, Syed N, Tzakos AG. Tsiailanis AD, et al. Among authors: widdop re. Free Radic Biol Med. 2020 Nov 20;160:391-402. doi: 10.1016/j.freeradbiomed.2020.08.007. Epub 2020 Aug 18. Free Radic Biol Med. 2020. PMID: 32822744
Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.
Magnani F, Pappas CG, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis IP, Tamura M, Widdop RE, Tzakos AG. Magnani F, et al. Among authors: widdop re. ACS Chem Biol. 2014 Jul 18;9(7):1420-5. doi: 10.1021/cb500063y. Epub 2014 May 14. ACS Chem Biol. 2014. PMID: 24787922 Free PMC article.
β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats.
Del Borgo M, Wang Y, Bosnyak S, Khan M, Walters P, Spizzo I, Perlmutter P, Hilliard L, Denton K, Aguilar MI, Widdop RE, Jones ES. Del Borgo M, et al. Among authors: widdop re. Clin Sci (Lond). 2015 Sep;129(6):505-13. doi: 10.1042/CS20150077. Epub 2015 May 8. Clin Sci (Lond). 2015. PMID: 26186568
Anti-fibrotic Potential of AT2 Receptor Agonists.
Wang Y, Del Borgo M, Lee HW, Baraldi D, Hirmiz B, Gaspari TA, Denton KM, Aguilar MI, Samuel CS, Widdop RE. Wang Y, et al. Among authors: widdop re. Front Pharmacol. 2017 Aug 31;8:564. doi: 10.3389/fphar.2017.00564. eCollection 2017. Front Pharmacol. 2017. PMID: 28912715 Free PMC article. Review.
171 results