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Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2.
Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, Ogohara C, Palser A, Chalk S, Lee EC, Kepl E, Chow CM, Sydeman C, Hodge EA, Brown B, Fuller JT, Dinnon KH 3rd, Gralinski LE, Leist SR, Gully KL, Lewis TB, Guttman M, Chu HY, Lee KK, Fuller DH, Baric RS, Kellam P, Carter L, Pepper M, Sheahan TP, Veesler D, King NP. Walls AC, et al. Among authors: fuller jt, fuller dh. bioRxiv [Preprint]. 2020 Aug 12:2020.08.11.247395. doi: 10.1101/2020.08.11.247395. bioRxiv. 2020. Update in: Cell. 2020 Nov 25;183(5):1367-1382.e17. doi: 10.1016/j.cell.2020.10.043 PMID: 32817941 Free PMC article. Updated. Preprint.
Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D. Strauch EM, et al. Among authors: fuller dh. Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12. Nat Biotechnol. 2017. PMID: 28604661 Free PMC article.
Mucosal T Helper 17 and T Regulatory Cell Homeostasis Correlate with Acute Simian Immunodeficiency Virus Viremia and Responsiveness to Antiretroviral Therapy in Macaques.
O'Connor MA, Munson PV, Tunggal HC, Hajari N, Lewis TB, Bratt D, Moats C, Smedley J, Bagley KC, Mullins JI, Fuller DH. O'Connor MA, et al. Among authors: fuller dh. AIDS Res Hum Retroviruses. 2019 Mar;35(3):295-305. doi: 10.1089/AID.2018.0184. Epub 2019 Jan 2. AIDS Res Hum Retroviruses. 2019. PMID: 30398361 Free PMC article.
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates.
Erasmus JH, Khandhar AP, Walls AC, Hemann EA, O'Connor MA, Murapa P, Archer J, Leventhal S, Fuller J, Lewis T, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: fuller dh, fuller j. bioRxiv [Preprint]. 2020 May 28:2020.05.28.121640. doi: 10.1101/2020.05.28.121640. bioRxiv. 2020. PMID: 32511417 Free PMC article. Preprint.
An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.
Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: fuller jt, fuller dh. Sci Transl Med. 2020 Aug 5;12(555):eabc9396. doi: 10.1126/scitranslmed.abc9396. Epub 2020 Jul 20. Sci Transl Med. 2020. PMID: 32690628 Free PMC article.
De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M Jr, Blancas-Mejia LM, Yen HL, Silva DA. Linsky TW, et al. Among authors: fuller dh. Science. 2020 Dec 4;370(6521):1208-1214. doi: 10.1126/science.abe0075. Epub 2020 Nov 5. Science. 2020. PMID: 33154107 Free PMC article.
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.
Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, Ogohara C, Palser A, Chalk S, Lee EC, Guerriero K, Kepl E, Chow CM, Sydeman C, Hodge EA, Brown B, Fuller JT, Dinnon KH 3rd, Gralinski LE, Leist SR, Gully KL, Lewis TB, Guttman M, Chu HY, Lee KK, Fuller DH, Baric RS, Kellam P, Carter L, Pepper M, Sheahan TP, Veesler D, King NP. Walls AC, et al. Among authors: fuller jt, fuller dh. Cell. 2020 Nov 25;183(5):1367-1382.e17. doi: 10.1016/j.cell.2020.10.043. Epub 2020 Oct 31. Cell. 2020. PMID: 33160446 Free PMC article.
Recrudescence of Natural Coccidioidomycosis During Combination Antiretroviral Therapy in a Pigtail Macaque Experimentally Infected with Simian Immunodeficiency Virus.
Guerriero KA, Murnane RD, Lewis TB, Brown B, Baldessari A, Jeffery DA, Malinowski CM, Fuller DH, O'Connor MA. Guerriero KA, et al. Among authors: fuller dh. AIDS Res Hum Retroviruses. 2021 Jul;37(7):505-509. doi: 10.1089/AID.2020.0228. Epub 2021 Feb 23. AIDS Res Hum Retroviruses. 2021. PMID: 33356854 Free PMC article.
A Gut Reaction to SIV and SHIV Infection: Lower Dysregulation of Mucosal T Cells during Acute Infection Is Associated with Greater Viral Suppression during cART.
O'Connor MA, Munson PV, Dross SE, Tunggal HC, Lewis TB, Osborn J, Peterson CW, Huang MW, Moats C, Smedley J, Jerome KR, Kiem HP, Bagley KC, Mullins JI, Fuller DH. O'Connor MA, et al. Among authors: fuller dh. Viruses. 2021 Aug 14;13(8):1609. doi: 10.3390/v13081609. Viruses. 2021. PMID: 34452474 Free PMC article.
103 results