Welsch S - Search Results

1

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.

Turoňová B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, von Bülow S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Landry J, de Azevedo NTD, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M. Turoňová B, et al. Among authors: welsch s. Science. 2020 Oct 9;370(6513):203-208. doi: 10.1126/science.abd5223. Epub 2020 Aug 18. Science. 2020. PMID: 32817270 Free PMC article.

2

The vaccinia virus I3L gene product is localized to a complex endoplasmic reticulum-associated structure that contains the viral parental DNA.

Welsch S, Doglio L, Schleich S, Krijnse Locker J. Welsch S, et al. J Virol. 2003 May;77(10):6014-28. doi: 10.1128/jvi.77.10.6014-6028.2003. J Virol. 2003. PMID: 12719593 Free PMC article.

3

Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function.

Welsch S, Habermann A, Jäger S, Müller B, Krijnse-Locker J, Kräusslich HG. Welsch S, et al. Traffic. 2006 Nov;7(11):1551-66. doi: 10.1111/j.1600-0854.2006.00489.x. Epub 2006 Oct 2. Traffic. 2006. PMID: 17014699 Free article.

4

Composition and three-dimensional architecture of the dengue virus replication and assembly sites.

Welsch S, Miller S, Romero-Brey I, Merz A, Bleck CK, Walther P, Fuller SD, Antony C, Krijnse-Locker J, Bartenschlager R. Welsch S, et al. Cell Host Microbe. 2009 Apr 23;5(4):365-75. doi: 10.1016/j.chom.2009.03.007. Cell Host Microbe. 2009. PMID: 19380115 Free PMC article.

5

Open membranes are the precursors for assembly of large DNA viruses.

Suárez C, Welsch S, Chlanda P, Hagen W, Hoppe S, Kolovou A, Pagnier I, Raoult D, Krijnse Locker J. Suárez C, et al. Among authors: welsch s. Cell Microbiol. 2013 Nov;15(11):1883-95. doi: 10.1111/cmi.12156. Epub 2013 Jul 5. Cell Microbiol. 2013. PMID: 23751082 Free PMC article.

6

The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.

Safarian S, Opel-Reading HK, Wu D, Mehdipour AR, Hards K, Harold LK, Radloff M, Stewart I, Welsch S, Hummer G, Cook GM, Krause KL, Michel H. Safarian S, et al. Among authors: welsch s. Nat Commun. 2021 Sep 2;12(1):5236. doi: 10.1038/s41467-021-25537-z. Nat Commun. 2021. PMID: 34475399 Free PMC article.

7

Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism.

Khera R, Mehdipour AR, Bolla JR, Kahnt J, Welsch S, Ermler U, Muenke C, Robinson CV, Hummer G, Xie H, Michel H. Khera R, et al. Among authors: welsch s. EMBO J. 2022 Sep 15;41(18):e109990. doi: 10.15252/embj.2021109990. Epub 2022 Jun 14. EMBO J. 2022. PMID: 35698912 Free PMC article.

8

Structures of the eukaryotic ribosome and its translational states in situ.

Hoffmann PC, Kreysing JP, Khusainov I, Tuijtel MW, Welsch S, Beck M. Hoffmann PC, et al. Among authors: welsch s. Nat Commun. 2022 Dec 2;13(1):7435. doi: 10.1038/s41467-022-34997-w. Nat Commun. 2022. PMID: 36460643 Free PMC article.

9

Dissecting the conformational complexity and mechanism of a bacterial heme transporter.

Wu D, Mehdipour AR, Finke F, Goojani HG, Groh RR, Grund TN, Reichhart TMB, Zimmermann R, Welsch S, Bald D, Shepherd M, Hummer G, Safarian S. Wu D, et al. Among authors: welsch s. Nat Chem Biol. 2023 Aug;19(8):992-1003. doi: 10.1038/s41589-023-01314-5. Epub 2023 Apr 24. Nat Chem Biol. 2023. PMID: 37095238 Free PMC article.

10

Translation dynamics in human cells visualized at high resolution reveal cancer drug action.

Xing H, Taniguchi R, Khusainov I, Kreysing JP, Welsch S, Turoňová B, Beck M. Xing H, et al. Among authors: welsch s. Science. 2023 Jul 7;381(6653):70-75. doi: 10.1126/science.adh1411. Epub 2023 Jul 6. Science. 2023. PMID: 37410833

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