Kozikowski AP - Search Results

1

Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.

Noonepalle S, Shen S, Ptáček J, Tavares MT, Zhang G, Stránský J, Pavlíček J, Ferreira GM, Hadley M, Pelaez G, Bařinka C, Kozikowski AP, Villagra A. Noonepalle S, et al. Among authors: kozikowski ap. J Med Chem. 2020 Sep 24;63(18):10246-10262. doi: 10.1021/acs.jmedchem.0c00567. Epub 2020 Sep 2. J Med Chem. 2020. PMID: 32815366

2

Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.

Bergman JA, Woan K, Perez-Villarroel P, Villagra A, Sotomayor EM, Kozikowski AP. Bergman JA, et al. Among authors: kozikowski ap. J Med Chem. 2012 Nov 26;55(22):9891-9. doi: 10.1021/jm301098e. Epub 2012 Oct 23. J Med Chem. 2012. PMID: 23009203 Free PMC article.

3

Why Hydroxamates May Not Be the Best Histone Deacetylase Inhibitors--What Some May Have Forgotten or Would Rather Forget?

Shen S, Kozikowski AP. Shen S, et al. Among authors: kozikowski ap. ChemMedChem. 2016 Jan 5;11(1):15-21. doi: 10.1002/cmdc.201500486. Epub 2015 Nov 25. ChemMedChem. 2016. PMID: 26603496 Free PMC article.

4

Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors.

Lv W, Zhang G, Barinka C, Eubanks JH, Kozikowski AP. Lv W, et al. Among authors: kozikowski ap. ACS Med Chem Lett. 2017 Apr 7;8(5):510-515. doi: 10.1021/acsmedchemlett.7b00012. eCollection 2017 May 11. ACS Med Chem Lett. 2017. PMID: 28523102 Free PMC article.

5

A patent review of histone deacetylase 6 inhibitors in neurodegenerative diseases (2014-2019).

Shen S, Kozikowski AP. Shen S, et al. Among authors: kozikowski ap. Expert Opin Ther Pat. 2020 Feb;30(2):121-136. doi: 10.1080/13543776.2019.1708901. Epub 2019 Dec 25. Expert Opin Ther Pat. 2020. PMID: 31865813 Free PMC article. Review.

6

Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models.

Tavares MT, Shen S, Knox T, Hadley M, Kutil Z, Bařinka C, Villagra A, Kozikowski AP. Tavares MT, et al. Among authors: kozikowski ap. ACS Med Chem Lett. 2017 Sep 5;8(10):1031-1036. doi: 10.1021/acsmedchemlett.7b00223. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057046 Free PMC article.

7

Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor.

Porter NJ, Shen S, Barinka C, Kozikowski AP, Christianson DW. Porter NJ, et al. Among authors: kozikowski ap. ACS Med Chem Lett. 2018 Nov 21;9(12):1301-1305. doi: 10.1021/acsmedchemlett.8b00487. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613344 Free PMC article.

8

Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.

Shen S, Hadley M, Ustinova K, Pavlicek J, Knox T, Noonepalle S, Tavares MT, Zimprich CA, Zhang G, Robers MB, Bařinka C, Kozikowski AP, Villagra A. Shen S, et al. Among authors: kozikowski ap. J Med Chem. 2019 Sep 26;62(18):8557-8577. doi: 10.1021/acs.jmedchem.9b00946. Epub 2019 Sep 4. J Med Chem. 2019. PMID: 31414801

9

Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor.

Shen S, Svoboda M, Zhang G, Cavasin MA, Motlova L, McKinsey TA, Eubanks JH, Bařinka C, Kozikowski AP. Shen S, et al. Among authors: kozikowski ap. ACS Med Chem Lett. 2020 Jan 15;11(5):706-712. doi: 10.1021/acsmedchemlett.9b00560. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435374 Free PMC article.

10

Mercaptoacetamide: A promising zinc-binding group for the discovery of selective histone deacetylase 6 inhibitors.

Tavares MT, Kozikowski AP, Shen S. Tavares MT, et al. Among authors: kozikowski ap. Eur J Med Chem. 2021 Jan 1;209:112887. doi: 10.1016/j.ejmech.2020.112887. Epub 2020 Sep 29. Eur J Med Chem. 2021. PMID: 33035922 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

346 results

Search Page

Filters