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Dual Parasiticidal Activities of Phthalimides: Synthesis and Biological Profile against Trypanosoma cruzi and Plasmodium falciparum.
Teixeira de Moraes Gomes PA, Veríssimo de Oliveira Cardoso M, Dos Santos IR, Amaro de Sousa F, da Conceição JM, Gouveia de Melo Silva V, Duarte D, Pereira R, Oliveira R, Nogueira F, Alves LC, Brayner FA, da Silva Santos AC, Rêgo Alves Pereira V, Lima Leite AC. Teixeira de Moraes Gomes PA, et al. ChemMedChem. 2020 Nov 18;15(22):2164-2175. doi: 10.1002/cmdc.202000331. Epub 2020 Oct 19. ChemMedChem. 2020. PMID: 32813331
Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC. Magalhaes Moreira DR, et al. Among authors: teixeira de moraes gomes pa. Eur J Med Chem. 2014 Mar 21;75:467-78. doi: 10.1016/j.ejmech.2014.02.001. Epub 2014 Feb 3. Eur J Med Chem. 2014. PMID: 24561675