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Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.
Sundberg M, Tochitsky I, Buchholz DE, Winden K, Kujala V, Kapur K, Cataltepe D, Turner D, Han MJ, Woolf CJ, Hatten ME, Sahin M. Sundberg M, et al. Among authors: tochitsky i. Mol Psychiatry. 2018 Nov;23(11):2167-2183. doi: 10.1038/s41380-018-0018-4. Epub 2018 Feb 15. Mol Psychiatry. 2018. PMID: 29449635 Free PMC article.
Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons.
Cheng YC, Snavely A, Barrett LB, Zhang X, Herman C, Frost DJ, Riva P, Tochitsky I, Kawaguchi R, Singh B, Ivanis J, Huebner EA, Arvanites A, Oza V, Davidow L, Maeda R, Sakuma M, Grantham A, Wang Q, Chang AN, Pfaff K, Costigan M, Coppola G, Rubin LL, Schwer B, Alt FW, Woolf CJ. Cheng YC, et al. Among authors: tochitsky i. Cell Rep. 2021 Sep 7;36(10):109666. doi: 10.1016/j.celrep.2021.109666. Cell Rep. 2021. PMID: 34496254 Free PMC article.
How Azobenzene Photoswitches Restore Visual Responses to the Blind Retina.
Tochitsky I, Helft Z, Meseguer V, Fletcher RB, Vessey KA, Telias M, Denlinger B, Malis J, Fletcher EL, Kramer RH. Tochitsky I, et al. Neuron. 2016 Oct 5;92(1):100-113. doi: 10.1016/j.neuron.2016.08.038. Epub 2016 Sep 22. Neuron. 2016. PMID: 27667006 Free PMC article.
Photochemical restoration of visual responses in blind mice.
Polosukhina A, Litt J, Tochitsky I, Nemargut J, Sychev Y, De Kouchkovsky I, Huang T, Borges K, Trauner D, Van Gelder RN, Kramer RH. Polosukhina A, et al. Among authors: tochitsky i. Neuron. 2012 Jul 26;75(2):271-82. doi: 10.1016/j.neuron.2012.05.022. Neuron. 2012. PMID: 22841312 Free PMC article.
LiGluR restores visual responses in rodent models of inherited blindness.
Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG. Caporale N, et al. Among authors: tochitsky i. Mol Ther. 2011 Jul;19(7):1212-9. doi: 10.1038/mt.2011.103. Epub 2011 May 24. Mol Ther. 2011. PMID: 21610698 Free PMC article.
19 results