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Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, Menis S, Alter G, Schief WR, Crotty S, King NP, Baker D, Silvestri G, Ward AB, Irvine DJ. Martin JT, et al. Among authors: silvestri g. NPJ Vaccines. 2020 Aug 5;5(1):72. doi: 10.1038/s41541-020-00223-1. eCollection 2020. NPJ Vaccines. 2020. PMID: 32802411 Free PMC article.
A Blueprint for HIV Vaccine Discovery.
Burton DR, Ahmed R, Barouch DH, Butera ST, Crotty S, Godzik A, Kaufmann DE, McElrath MJ, Nussenzweig MC, Pulendran B, Scanlan CN, Schief WR, Silvestri G, Streeck H, Walker BD, Walker LM, Ward AB, Wilson IA, Wyatt R. Burton DR, et al. Among authors: silvestri g. Cell Host Microbe. 2012 Oct 18;12(4):396-407. doi: 10.1016/j.chom.2012.09.008. Cell Host Microbe. 2012. PMID: 23084910 Free PMC article. Review.
Immunological and virological analyses of rhesus macaques immunized with chimpanzee adenoviruses expressing the simian immunodeficiency virus Gag/Tat fusion protein and challenged intrarectally with repeated low doses of SIVmac.
Cervasi B, Carnathan DG, Sheehan KM, Micci L, Paiardini M, Kurupati R, Tuyishime S, Zhou XY, Else JG, Ratcliffe SJ, Ertl HC, Silvestri G. Cervasi B, et al. Among authors: silvestri g. J Virol. 2013 Sep;87(17):9420-30. doi: 10.1128/JVI.01456-13. Epub 2013 Jun 26. J Virol. 2013. PMID: 23804645 Free PMC article.
Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.
Chahroudi A, Cartwright E, Lee ST, Mavigner M, Carnathan DG, Lawson B, Carnathan PM, Hashempoor T, Murphy MK, Meeker T, Ehnert S, Souder C, Else JG, Cohen J, Collman RG, Vanderford TH, Permar SR, Derdeyn CA, Villinger F, Silvestri G. Chahroudi A, et al. Among authors: silvestri g. PLoS Pathog. 2014 Mar 6;10(3):e1003958. doi: 10.1371/journal.ppat.1003958. eCollection 2014 Mar. PLoS Pathog. 2014. PMID: 24604066 Free PMC article.
Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques.
Carnathan DG, Wetzel KS, Yu J, Lee ST, Johnson BA, Paiardini M, Yan J, Morrow MP, Sardesai NY, Weiner DB, Ertl HC, Silvestri G. Carnathan DG, et al. Among authors: silvestri g. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):518-23. doi: 10.1073/pnas.1407466112. Epub 2014 Dec 30. Proc Natl Acad Sci U S A. 2015. PMID: 25550504 Free PMC article.
Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques.
Moldt B, Le KM, Carnathan DG, Whitney JB, Schultz N, Lewis MG, Borducchi EN, Smith KM, Mackel JJ, Sweat SL, Hodges AP, Godzik A, Parren PW, Silvestri G, Barouch DH, Burton DR. Moldt B, et al. Among authors: silvestri g. AIDS. 2016 Jun 19;30(10):1543-51. doi: 10.1097/QAD.0000000000001102. AIDS. 2016. PMID: 27243773 Free PMC article.
1,087 results