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Genome-wide microRNA profiling of plasma from three different animal models identifies biomarkers of temporal lobe epilepsy.
Brennan GP, Bauer S, Engel T, Jimenez-Mateos EM, Del Gallo F, Hill TDM, Connolly NMC, Costard LS, Neubert V, Salvetti B, Sanz-Rodriguez A, Heiland M, Mamad O, Brindley E, Norwood B, Batool A, Raoof R, El-Naggar H, Reschke CR, Delanty N, Prehn JHM, Fabene P, Mooney C, Rosenow F, Henshall DC. Brennan GP, et al. Among authors: hill tdm. Neurobiol Dis. 2020 Oct;144:105048. doi: 10.1016/j.nbd.2020.105048. Epub 2020 Aug 13. Neurobiol Dis. 2020. PMID: 32800995 Free article.
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control.
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC. Heiland M, et al. Among authors: hill tdm. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2216658120. doi: 10.1073/pnas.2216658120. Epub 2023 Jul 18. Proc Natl Acad Sci U S A. 2023. PMID: 37463203 Free PMC article.
Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy.
Brindley E, Heiland M, Mooney C, Diviney M, Mamad O, Hill TDM, Yan Y, Venø MT, Reschke CR, Batool A, Langa E, Sanz-Rodriguez A, Heller JP, Morris G, Conboy K, Kjems J, Brennan GP, Henshall DC. Brindley E, et al. Among authors: hill tdm. Front Mol Neurosci. 2023 Sep 22;16:1230942. doi: 10.3389/fnmol.2023.1230942. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37808470 Free PMC article.
Anti-seizure effects of JNJ-54175446 in the intra-amygdala kainic acid model of drug-resistant temporal lobe epilepsy in mice.
Mamad O, Heiland M, Lindner AU, Hill TDM, Ronroy RM, Rentrup K, Sanz-Rodriguez A, Langa E, Heller JP, Moreno O, Llop J, Bhattacharya A, Palmer JA, Ceusters M, Engel T, Henshall DC. Mamad O, et al. Among authors: hill tdm. Front Pharmacol. 2024 Jan 8;14:1308478. doi: 10.3389/fphar.2023.1308478. eCollection 2023. Front Pharmacol. 2024. PMID: 38259288 Free PMC article.
Cannabidivarin is anticonvulsant in mouse and rat.
Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ. Hill AJ, et al. Br J Pharmacol. 2012 Dec;167(8):1629-42. doi: 10.1111/j.1476-5381.2012.02207.x. Br J Pharmacol. 2012. PMID: 22970845 Free PMC article.
11 results