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Pharmacokinetic/pharmacodynamic considerations for new and current therapeutic drugs for uncomplicated gonorrhoea-challenges and opportunities.
Theuretzbacher U, Barbee L, Connolly K, Drusano G, Fernandes P, Hook E, Jerse A, O'Donnell J, Unemo M, Van Bambeke F, VanScoy B, Warn P, Werth BJ, Franceschi F, Alirol E. Theuretzbacher U, et al. Among authors: alirol e. Clin Microbiol Infect. 2020 Dec;26(12):1630-1635. doi: 10.1016/j.cmi.2020.08.006. Epub 2020 Aug 13. Clin Microbiol Infect. 2020. PMID: 32798687 Free article. Review.
Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.
Alirol E, Wi TE, Bala M, Bazzo ML, Chen XS, Deal C, Dillon JR, Kularatne R, Heim J, Hooft van Huijsduijnen R, Hook EW, Lahra MM, Lewis DA, Ndowa F, Shafer WM, Tayler L, Workowski K, Unemo M, Balasegaram M. Alirol E, et al. PLoS Med. 2017 Jul 26;14(7):e1002366. doi: 10.1371/journal.pmed.1002366. eCollection 2017 Jul. PLoS Med. 2017. PMID: 28746372 Free PMC article.
High in vitro susceptibility to the first-in-class spiropyrimidinetrione zoliflodacin among consecutive clinical Neisseria gonorrhoeae isolates from Thailand (2018) and South Africa (2015-2017).
Jacobsson S, Kularatne R, Kittiyaowamarn R, Maseko V, Paopang P, Sangprasert P, Sirivongrangson P, Piddock L, Wi T, Alirol E, Unemo M. Jacobsson S, et al. Among authors: alirol e. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01479-19. doi: 10.1128/AAC.01479-19. Epub 2019 Sep 23. Antimicrob Agents Chemother. 2019. PMID: 31548184 Free PMC article.
In vitro antimicrobial combination testing of and evolution of resistance to the first-in-class spiropyrimidinetrione zoliflodacin combined with six therapeutically relevant antimicrobials for Neisseria gonorrhoeae.
Foerster S, Drusano G, Golparian D, Neely M, Piddock LJV, Alirol E, Unemo M. Foerster S, et al. Among authors: alirol e. J Antimicrob Chemother. 2019 Dec 1;74(12):3521-3529. doi: 10.1093/jac/dkz376. J Antimicrob Chemother. 2019. PMID: 31730160
Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model.
Jacobsson S, Golparian D, Oxelbark J, Alirol E, Franceschi F, Gustafsson TN, Brown D, Louie A, Drusano G, Unemo M. Jacobsson S, et al. Among authors: alirol e. Front Pharmacol. 2021 May 21;12:682135. doi: 10.3389/fphar.2021.682135. eCollection 2021. Front Pharmacol. 2021. PMID: 34093206 Free PMC article.
Rapid diagnostic tests for non-malarial febrile illness in the tropics.
Chappuis F, Alirol E, d'Acremont V, Bottieau E, Yansouni CP. Chappuis F, et al. Among authors: alirol e. Clin Microbiol Infect. 2013 May;19(5):422-31. doi: 10.1111/1469-0691.12154. Epub 2013 Feb 15. Clin Microbiol Infect. 2013. PMID: 23413992 Free article. Review.
36 results