The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells.
Wolf G, Craigon C, Teoh ST, Essletzbichler P, Onstein S, Cassidy D, Uijttewaal ECH, Dvorak V, Cao Y, Bensimon A, Elling U, Ciulli A, Superti-Furga G.
Wolf G, et al. Among authors: cao y.
Cell Chem Biol. 2024 Dec 24:S2451-9456(24)00489-6. doi: 10.1016/j.chembiol.2024.11.009. Online ahead of print.
Cell Chem Biol. 2024.
PMID: 39755121