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An ATP-dependent partner switch links flagellar C-ring assembly with gene expression.
Blagotinsek V, Schwan M, Steinchen W, Mrusek D, Hook JC, Rossmann F, Freibert SA, Kratzat H, Murat G, Kressler D, Beckmann R, Beeby M, Thormann KM, Bange G. Blagotinsek V, et al. Among authors: freibert sa. Proc Natl Acad Sci U S A. 2020 Aug 25;117(34):20826-20835. doi: 10.1073/pnas.2006470117. Epub 2020 Aug 11. Proc Natl Acad Sci U S A. 2020. PMID: 32788349 Free PMC article.
Structural basis for (p)ppGpp-mediated inhibition of the GTPase RbgA.
Pausch P, Steinchen W, Wieland M, Klaus T, Freibert SA, Altegoer F, Wilson DN, Bange G. Pausch P, et al. Among authors: freibert sa. J Biol Chem. 2018 Dec 21;293(51):19699-19709. doi: 10.1074/jbc.RA118.003070. Epub 2018 Oct 26. J Biol Chem. 2018. PMID: 30366986 Free PMC article.
Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
Czech L, Mais CN, Kratzat H, Sarmah P, Giammarinaro P, Freibert SA, Esser HF, Musial J, Berninghausen O, Steinchen W, Beckmann R, Koch HG, Bange G. Czech L, et al. Among authors: freibert sa. Nat Commun. 2022 Feb 25;13(1):1069. doi: 10.1038/s41467-022-28675-0. Nat Commun. 2022. PMID: 35217658 Free PMC article.
The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture.
Eilers K, Hoong Yam JK, Liu X, Goh YF, To KN, Paracuellos P, Morton R, Brizuela J, Hui Yong AM, Givskov M, Freibert SA, Bange G, Rice SA, Steinchen W, Filloux A. Eilers K, et al. Among authors: freibert sa. J Biol Chem. 2024 Feb;300(2):105659. doi: 10.1016/j.jbc.2024.105659. Epub 2024 Jan 16. J Biol Chem. 2024. PMID: 38237678 Free PMC article.
32 results