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Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB. Antanasijevic A, et al. Among authors: huang d. PLoS Pathog. 2020 Aug 11;16(8):e1008665. doi: 10.1371/journal.ppat.1008665. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32780770 Free PMC article.
HIV-1 vaccine design through minimizing envelope metastability.
He L, Kumar S, Allen JD, Huang D, Lin X, Mann CJ, Saye-Francisco KL, Copps J, Sarkar A, Blizard GS, Ozorowski G, Sok D, Crispin M, Ward AB, Nemazee D, Burton DR, Wilson IA, Zhu J. He L, et al. Among authors: huang d. Sci Adv. 2018 Nov 21;4(11):eaau6769. doi: 10.1126/sciadv.aau6769. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30474059 Free PMC article.
Reprogramming the antigen specificity of B cells using genome-editing technologies.
Voss JE, Gonzalez-Martin A, Andrabi R, Fuller RP, Murrell B, McCoy LE, Porter K, Huang D, Li W, Sok D, Le K, Briney B, Chateau M, Rogers G, Hangartner L, Feeney AJ, Nemazee D, Cannon P, Burton DR. Voss JE, et al. Among authors: huang d. Elife. 2019 Jan 17;8:e42995. doi: 10.7554/eLife.42995. Elife. 2019. PMID: 30648968 Free PMC article.
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model.
Rogers TF, Zhao F, Huang D, Beutler N, Burns A, He WT, Limbo O, Smith C, Song G, Woehl J, Yang L, Abbott RK, Callaghan S, Garcia E, Hurtado J, Parren M, Peng L, Ramirez S, Ricketts J, Ricciardi MJ, Rawlings SA, Wu NC, Yuan M, Smith DM, Nemazee D, Teijaro JR, Voss JE, Wilson IA, Andrabi R, Briney B, Landais E, Sok D, Jardine JG, Burton DR. Rogers TF, et al. Among authors: huang d. Science. 2020 Aug 21;369(6506):956-963. doi: 10.1126/science.abc7520. Epub 2020 Jun 15. Science. 2020. PMID: 32540903 Free PMC article.
Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.
Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB. Bangaru S, et al. Among authors: huang d. bioRxiv [Preprint]. 2020 Aug 6:2020.08.06.234674. doi: 10.1101/2020.08.06.234674. bioRxiv. 2020. Update in: Science. 2020 Nov 27;370(6520):1089-1094. doi: 10.1126/science.abe1502 PMID: 32793901 Free PMC article. Updated. Preprint.
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models.
Huang D, Abbott RK, Havenar-Daughton C, Skog PD, Al-Kolla R, Groschel B, Blane TR, Menis S, Tran JT, Thinnes TC, Volpi SA, Liguori A, Schiffner T, Villegas SM, Kalyuzhniy O, Pintea M, Voss JE, Phelps N, Tingle R, Rodriguez AR, Martin G, Kupryianov S, deCamp A, Schief WR, Nemazee D, Crotty S. Huang D, et al. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22920-22931. doi: 10.1073/pnas.2004489117. Epub 2020 Sep 1. Proc Natl Acad Sci U S A. 2020. PMID: 32873644 Free PMC article.
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody.
Wu NC, Yuan M, Bangaru S, Huang D, Zhu X, Lee CD, Turner HL, Peng L, Yang L, Nemazee D, Ward AB, Wilson IA. Wu NC, et al. Among authors: huang d. bioRxiv [Preprint]. 2020 Sep 21:2020.09.21.305441. doi: 10.1101/2020.09.21.305441. bioRxiv. 2020. Update in: PLoS Pathog. 2020 Dec 4;16(12):e1009089. doi: 10.1371/journal.ppat.1009089 PMID: 32995788 Free PMC article. Updated. Preprint.
Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate.
Bangaru S, Ozorowski G, Turner HL, Antanasijevic A, Huang D, Wang X, Torres JL, Diedrich JK, Tian JH, Portnoff AD, Patel N, Massare MJ, Yates JR 3rd, Nemazee D, Paulson JC, Glenn G, Smith G, Ward AB. Bangaru S, et al. Among authors: huang d. Science. 2020 Nov 27;370(6520):1089-1094. doi: 10.1126/science.abe1502. Epub 2020 Oct 20. Science. 2020. PMID: 33082295 Free PMC article.
Commercial Serology Assays Predict Neutralization Activity against SARS-CoV-2.
Suhandynata RT, Hoffman MA, Huang D, Tran JT, Kelner MJ, Reed SL, McLawhon RW, Voss JE, Nemazee D, Fitzgerald RL. Suhandynata RT, et al. Among authors: huang d. Clin Chem. 2021 Jan 30;67(2):404-414. doi: 10.1093/clinchem/hvaa262. Clin Chem. 2021. PMID: 33084854 Free PMC article.
Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells.
Huang D, Tran JT, Olson A, Vollbrecht T, Tenuta M, Guryleva MV, Fuller RP, Schiffner T, Abadejos JR, Couvrette L, Blane TR, Saye K, Li W, Landais E, Gonzalez-Martin A, Schief W, Murrell B, Burton DR, Nemazee D, Voss JE. Huang D, et al. Nat Commun. 2020 Nov 17;11(1):5850. doi: 10.1038/s41467-020-19650-8. Nat Commun. 2020. PMID: 33203876 Free PMC article.
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