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Page 1
ERK5 signalling in prostate cancer promotes an invasive phenotype.
Ramsay AK, McCracken SR, Soofi M, Fleming J, Yu AX, Ahmad I, Morland R, Machesky L, Nixon C, Edwards DR, Nuttall RK, Seywright M, Marquez R, Keller E, Leung HY. Ramsay AK, et al. Br J Cancer. 2011 Feb 15;104(4):664-72. doi: 10.1038/sj.bjc.6606062. Epub 2011 Jan 25. Br J Cancer. 2011. PMID: 21266977 Free PMC article.
Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.
Li A, Ma Y, Yu X, Mort RL, Lindsay CR, Stevenson D, Strathdee D, Insall RH, Chernoff J, Snapper SB, Jackson IJ, Larue L, Sansom OJ, Machesky LM. Li A, et al. Among authors: machesky lm. Dev Cell. 2011 Oct 18;21(4):722-34. doi: 10.1016/j.devcel.2011.07.008. Epub 2011 Sep 15. Dev Cell. 2011. PMID: 21924960 Free PMC article.
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Lindsay CR, Lawn S, Campbell AD, Faller WJ, Rambow F, Mort RL, Timpson P, Li A, Cammareri P, Ridgway RA, Morton JP, Doyle B, Hegarty S, Rafferty M, Murphy IG, McDermott EW, Sheahan K, Pedone K, Finn AJ, Groben PA, Thomas NE, Hao H, Carson C, Norman JC, Machesky LM, Gallagher WM, Jackson IJ, Van Kempen L, Beermann F, Der C, Larue L, Welch HC, Ozanne BW, Sansom OJ. Lindsay CR, et al. Among authors: machesky lm. Nat Commun. 2011 Nov 22;2:555. doi: 10.1038/ncomms1560. Nat Commun. 2011. PMID: 22109529 Free PMC article.
Melanoblasts on the move: Rac1 sets the pace.
Li A, Machesky LM. Li A, et al. Among authors: machesky lm. Small GTPases. 2012 Apr-Jun;3(2):115-9. doi: 10.4161/sgtp.19494. Small GTPases. 2012. PMID: 22790200 Free article.
Rac1 in the driver's seat for melanoma.
Machesky LM, Sansom OJ. Machesky LM, et al. Pigment Cell Melanoma Res. 2012 Nov;25(6):762-4. doi: 10.1111/pcmr.12004. Pigment Cell Melanoma Res. 2012. PMID: 22882909 No abstract available.
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.
Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futó K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrády B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM. Yu X, et al. Among authors: machesky lm. J Cell Biol. 2012 Oct 29;199(3):527-44. doi: 10.1083/jcb.201203025. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091069 Free PMC article.
216 results